The Cochrane Library
Featured and Breaking News
Only half of patients take their medications as prescribed: are there interventions that will help them?
The cost of patients not taking their medications as prescribed can be substantial in terms of their health. Although a large amount of research evidence has tried to address this problem, there are no well-established approaches to help them, according to a new systematic review published in The Cochrane Library.
You selected: The Cochrane Library
A new study published today in The Cochrane Library, highlights the difficult decisions women with epilepsy have to face when they become pregnant. Taking certain drugs used to control epilepsy during pregnancy may be linked to developmental problems in children. The authors of the study say evidence on the safety of anti-epileptic drugs is limited and that more research is needed to ensure women and their doctors make the most informed choices.
When a woman is in labour, the appropriate time to give an epidural during childbirth is when she asks for it, a new study suggests. Published in The Cochrane Library, the systematic review compared early and late epidurals during labour and found that they had very similar effects.
Cheaper alternative to licensed drug for treating eye disease has similar side-effects says new Cochrane Review
Health policies which favour using ranibizumab for treating eye disease in older people over safety concerns for a cheaper alternative should take account of a new Cochrane Review published today.
Counselling techniques used to help young people with drinking problems may be of limited benefit, a new study suggests.
Shift workers are taking drugs to help them stay awake or get to sleep despite weak evidence for their benefit, according to a new Cochrane review. The authors of the review found only small numbers of trials testing over-the-counter and prescription drugs used by shift workers, and the results suggest that for some people they might do more harm than good.
Corticosteroid drugs that are given by inhalers to children with asthma may suppress their growth, evidence suggests. Two new systematic reviews published in The Cochrane Library focus on the effects of inhaled corticosteroid drugs (ICS) on growth rates. The authors found children’s growth slowed in the first year of treatment, although the effects were minimised by using lower doses.
In women with advanced (or metastatic) breast cancer, treatment with the breast cancer drug Trastuzumab (Herceptin®) is associated with prolonged survival but also increases the risk of developing heart problems, a new systematic review shows. However, the review, published in The Cochrane Library, concludes that more women benefit from use of Trastuzumab than are harmed.
Zinc supplements reduce diarrhoea and other infections in malnourished children, and may prevent death, according to a new study published in The Cochrane Library. The study is the first Cochrane systematic review to focus on zinc as a means to prevent childhood death, including deaths caused by diarrhoea, one of the biggest killers of under-fives.
Stem cell therapies work as a complement to standard treatments, potentially cutting the number of deaths after a year, suggests evidence from the latest Cochrane review: Stem cell therapy for chronic ischaemic heart disease and congestive heart failure. Taking stem cells from a patient’s bone marrow and injecting them into their damaged heart may be an effective way to treat heart disease.
Exercise may benefit older people with dementia by improving their cognitive functioning and ability to carry out everyday activities, according to a new systematic review published in The Cochrane Library. However, the authors of the review did not see any clear effect of exercise on depression in older people with dementia and say that more evidence is needed to understand how exercise could reduce the burden on family caregivers and health systems.
Disasters affect millions of people and cost billions of dollars, but people affected and those trying to help them don’t always have good access to the best information on what they might do. Evidence Aid will change this. It has just been awarded the 2013 Unorthodox Prize, for an extraordinary and innovative approach to improving the lives of the world’s most disadvantaged people.
Exercise may benefit people suffering from depression, according to an updated systematic review published in The Cochrane Library. The authors of the review found evidence to suggest that exercise reduces symptoms of depression, although they say more high quality trials are needed/
Maternity care that involves a midwife as the main care provider leads to better outcomes for most women, according to a systematic review published in The Cochrane Library. Researchers found that women who received continued care throughout pregnancy and birth from a small group of midwives were less likely to give birth pre-term and required fewer interventions during labour and birth than when their care was shared between different obstetricians, GPs and midwives.
There is no high quality evidence that antioxidant supplements help to increase a woman’s chances of having a baby, according to the results of a new systematic review. The review, published in The Cochrane Library, found women were no more likely to conceive when taking oral antioxidants and that there was limited information about potential harms.
Improving water quality and hygiene practices may improve the growth of children, according to a new report. The Cochrane review – authored by the London School of Hygiene & Tropical Medicine and WaterAid – found evidence of small but significant improvements in growth of children under the age of five who have access to clean water and soap.
Delaying clamping of the umbilical cord after birth benefits newborn babies, according to a systematic review published in The Cochrane Library. The authors found babies’ blood and iron levels were healthier when the cord was clamped later.
Probiotic supplements have the potential to prevent diarrhoea caused by antibiotics, according to a new Cochrane systematic review. The authors studied Clostridium difficile (C. difficile) infections in patients taking antibiotics and found symptoms of diarrhoea were substantially reduced when patients were also treated with probiotics.
Nicotine replacement therapy and other licensed drugs can help people quit smoking, according to a new systematic review published in The Cochrane Library. The study, which is an overview of previous Cochrane reviews, supports the use of the smoking cessation medications that are already widely licensed internationally, and shows that another drug licensed in Russia could hold potential as an effective and affordable treatment.
Research into the complementary therapies evening primrose oil and borage oil shows little, if any, benefit for people with eczema compared with placebo, according to a new systematic review. The authors, who published their review in The Cochrane Library, conclude that further studies on the therapies would be difficult to justify.