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New research indicates that about one-quarter of patients with bladder cancer treated with radical surgery on curative intent have detectable levels of tumour cells circulating in their blood. The presence of circulating tumour cells was also a predictor of cancer recurrence and death.
Many patients who have their prostate glands removed as a treatment for prostate cancer complain of shortening in the length of the penis.
Many individuals with type 2 diabetes produce abnormally low levels of a gut hormone called GLP-1, which normally stimulates insulin release from the pancreas.
Direct Radiolabeling of Nanomaterials: Directly radiolabeled nanographene materials without chelators are suitable for bioimaging applications
Positron emission tomography plays a pivotal role for monitoring the distribution and accumulation of radiolabeled nanomaterials in living subjects. The radioactive metals are usually connected to the nanomaterial through an anchor, a so-called chelator, but this chemical binding can be omitted if nanographene is used, as American scientists report in the journal Angewandte Chemie. The replacement of chelator-based labeling by intrinsic labeling significantly enhances the bioimaging accuracy and reduces biases.
An updated Cochrane Review published today has identified effective and safe ways to reduce unnecessary use of antibiotics in hospitals. Guidelines and policies that promote better targeting of antibiotics in patients who need them have the greatest impact when they are supported by the most effective ways to change doctors’ behaviour.
In an analysis of more than 18,000 patients treated for colon cancer, current smokers were 14 percent more likely to die from their colon cancer within five years than patients who had never smoked.
A recent analysis found that among 990 individuals fatally shot by US police officers in 2015, Black civilians were more than twice as likely as White civilians to have been unarmed, and civilians from “other” minority groups were significantly more likely than White civilians to have not posed an imminent threat to the officer(s) or other civilians.
A new study indicates that the antiviral drug oseltamivir can reduce influenza infections and prevent deaths in a cost-saving manner under most pandemic scenarios.
Gastric bypass surgery is one of the most successful treatments for obesity and related disorders; however, some patients may not want to undergo surgery.
Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis. A new analysis indicates that following screening guidelines for HCC in cirrhotic patients is lifesaving and cost-effective compared with ‘real life’ monitoring.
Many older adults with newly diagnosed epilepsy in the United States are being prescribed older anti-epileptic drugs (AEDs), and only half begin treatment with AEDs within the first 30 days of a potential epilepsy diagnosis.
In a study of hip fracture patients, men displayed greater levels of cognitive impairment within the first 22 days of fracture than women, and cognitive limitations increased the risk of dying within six months in both men and women.
A national study from England indicates that older women are often not offered immediate breast reconstruction following a mastectomy, even though guidelines state that surgeons should discuss reconstruction with all suitable patients and that it should be available at the initial surgical operation.
A new study has found that poor strength in the thigh muscles may increase the risk of knee osteoarthritis in women but not men. This relationship was confounded by body mass index (BMI), which itself is known as a risk factor for knee osteoarthritis.
For reasons that are unclear, males are diagnosed with dyslexia more often than females. Researchers have now found that this may be due to males’ lower average and more variable reading performance relative to females’.
In a study of patients with Paget’s disease of bone—a common skeletal disorder that can lead to bone deformity, fractures, osteoarthritis, and bone pain—long-term intensive bisphosphonate therapy conferred no clinical benefit over giving bisphosphonates only when patients felt bone pain.
Expansion of exclusive relationship with Mattersight drives deeper student interaction, insights and improved outcomes for Wiley’s university partners
Hoboken, NJ— February 6 2017—John Wiley & Sons Inc. (NYSE: JWa and JWb), is pleased to announce the launch of a content sharing pilot on Wiley Online Library.
A recent analysis showed that although adult survivors of childhood cancer did not differ overall from their peers in terms of their satisfaction with their sex lives and romantic relationships, those who received cancer treatments that were especially toxic to the nervous system were least likely to have had intercourse, be in a relationship, or have children.
Pharmaceuticals from a Coal Mine? Novel microbial geldanamycin derivatives and cyclopentenone ansamycins from an abandoned coal mine
Digging around in the dark can sometimes lead to interesting results: in the acidic waters of an abandoned coal mine in Kentucky (USA), researchers discovered ten previously unknown microbial natural products from a strain of Streptomyces. They have now introduced these compounds in the journal Angewandte Chemie. Four of the molecules contain a cyclopentenone ring, which is rare in this class of substances.