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Adding sulphonylureas (SUs) to metformin remains a commonly used strategy for treating type 2 diabetes, but individual SUs differ and may confer different risks of abnormally low blood sugar, or hypoglycemia. SUs—which include newer generation agents such as gliclazide, glipizide, glimepiride, and glibenclamide—stimulate the production of insulin in the pancreas and increase the effectiveness of insulin in the body.
Researchers have discovered a protein that stimulates secretion of ghrelin, an appetite-stimulating hormone produced in the stomach. When fed to mice, the protein, called soy-ghretropin, increased blood levels of ghrelin and boosted their appetite.
A new study has revealed a relationship between chronic periodontitis and lacunar infarct, two common diseases in the elderly. Chronic periodontitis is an inflammatory disease of the gums, whereas lacunar infarct is a type of cerebral small vessel disease that can lead to a stroke.
A new study from Belgium indicates that the majority of community-dwelling elderly adults are taking prescription medications inappropriately. The study, which is published in the British Journal of Clinical Pharmacology, also found a link between underuse—not taking essential medications—and an increased risk of dying or needing to be hospitalized.
Wiley Announces Publication of THE SALES BOSS: The Real Secret to Hiring, Training, and Managing a Sales Team
The step-by-step guide to a winning sales team
A study of patients undergoing corneal transplants indicates that subtle differences between men and women may lead to poorer outcomes for a woman who has received a cornea from a male donor. The findings, which are published in the American Journal of Transplantation, suggest that gender matching may be beneficial to potentially reduce the risk of failure and rejection in patients undergoing corneal transplantation.
DNA polymerases are the “Xerox machines” that replicate our DNA. They must work with great precision to keep errors from creeping into our genes. In spite of this precision, they still accept building blocks that have been coupled to large proteins, as a group of German scientists reports in the journal Angewandte Chemie. Based on this fact, the team has developed detection systems for genotyping DNA and RNA that can be evaluated by the naked eye. This method may allow for new diagnostic tools for use in the field.
John Wiley and Sons Inc. announced today that it has been selected by the International Federation of Gynecology and Obstetrics (FIGO) as its publishing partner for its distinguished publication, the International Journal of Gynecology & Obstetrics (IJGO). This agreement, commencing in January 2017, will see the Journal move to the Wiley Online Library platform.
Counting Red Blood Cells: Electrochemical determination of the concentration and peroxidase activity of erythrocytes
Blood counts are routinely carried out before operations, in cases of infection, or when testing for a variety of diseases, such as anemia and leukemia. A key value in this test is the number of red blood cells (erythrocytes). Scientists at the University of Oxford (UK) have now introduced a simple nano-electrochemical process for the rapid, precise determination of the erythrocyte count. As described in the journal Angewandte Chemie, the test also determines the activity of individual erythrocytes toward hydrogen peroxide.
A new study indicates that individuals with diabetes may have an elevated risk of developing cancer before and immediately after a diabetes diagnosis. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings point to the need for a better understanding of the link between diabetes and cancer.
Facile Dosimetry for Chemical Hazards: Disposable, low-cost chemidosimetric indicator with smartphone connection
The detection of exposure to chemical hazards can save lives. American scientists have developed a smart and simple chemidosimeter based on a chemiresistive sensor combined with a near-field communication tag, which can be read-out by a smartphone. This chemically actuated resonant device (CARD) is made of simple components, is disposable, ready-to-use, needs no batteries, and can be worn as a badge by people who are likely exposed to chemical hazards. It is described in the journal Angewandte Chemie.
John Wiley & Sons, Inc., (NYSE: JWa, JWb) today announced the addition of Archana Singh as Executive Vice President and Chief Human Resource Officer.
Consistently watching high levels of television during childhood and adolescence were linked with lower peak bone mass at age 20 years in a recent study.
Research suggests that the application of current to the brain—known as transcranial direct current stimulation (tDCS)—may enhance cognition and lessen symptoms of depression, anxiety, and other conditions. While tDCS devices can be built with simple tools, experts are cautioning do-it-yourself users that there may be hidden risks.
An organizational approach to more effective school leadership, online and off
Mark Horstman identifies what "effective management" actually looks like, and digs into the four critical behaviors that make a manager great and explains how leaders can adjust their own behavior to be the leader every team needs.
In 2005, the National Institute for Health and Care Excellence (NICE) in England and Wales provided new guidance on the use of anti-osteoporosis therapies for the prevention of additional fractures in patients who had experienced osteoporotic fractures, which was followed by market authorization of a generic form of alendronic acid.
Researchers at several different US sites have found that less than one-third of 1% of patients infected with hepatitis B virus (HBV) get rid of the virus per year, and overall, only 1.2% of patients finally get rid of it.
Long-term use of antiepileptic drugs is a significant risk factor for vitamin D deficiency in children with epilepsy. A new Epilepsia study found that despite living in the tropics, a high proportion of Malaysian children with epilepsy are at risk of vitamin D deficiency.
Poor physical performance was linked with an increased risk of developing dementia in a study of individuals aged 90 and older who were followed for an average of 2.6 years.