Arthritis & Rheumatology
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Two new studies provide valuable insights into the treatment of different types of vasculitis, which are conditions that cause blood vessels to become inflamed. In the studies, which appear in Arthritis & Rheumatology, investigators examine whether a medication that interferes with the activity of certain immune cells may help treat the most common form of vasculitis, as well as one of the rarest forms, both of which affect the large blood vessels.
Chondroitin sulfate + glucosamine sulfate may provide no benefits for patients with knee osteoarthritis
Chondroitin sulfate (CS) plus glucosamine sulfate (GS) was no better than placebo for reducing pain and function impairment in a multicenter, randomized, double-blinded, placebo-controlled study of 164 patients with knee osteoarthritis.
Sleep apnea may increase the risk of developing gout, a new study shows.
Study Shows the Effects of Rare Autoimmune Diseases on the Health of Pregnant Women and their Babies
In a recent analysis of 2001 to 2011 data from Australia, pregnant women with rare autoimmune diseases had a higher likelihood of developing conditions such as hypertensive and bleeding disorders and required longer hospitalization at delivery than other pregnant women
Developing arthritis increases the risk of falling into poverty, especially for women, new research shows.
Contrary to recent reports, Boston-based researchers found that osteoarthritis patients who had total knee or hip joint replacement surgery, known as arthroplasty, were at increased risk of heart attack (myocardial infarction) in the early post-operative period. However, findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), indicate that long-term risk of heart attack did not persist, while the risk for venous thromboembolism—blood clot in veins and lungs—remained years after the procedure.
In a new study that assessed the effects of total knee replacement in rheumatoid arthritis patients versus osteoarthritis patients, researchers found that the surgery is highly effective in reducing knee pain and also provides benefits in other subjective quality of life indices in patients with rheumatoid arthritis. Improvements were not as great as those experienced by osteoarthritis patients, however.
In contrast to the general population, low body mass index has been associated with premature death in patients with rheumatoid arthritis —a situation known as the “obesity paradox.” A new Arthritis & Rheumatology study shows that weight loss, as opposed to low body mass index per se, is a strong predictor of mortality in these patients.
The first national investigation of Medicare coverage of biologic disease modifying drugs (DMARDs) found that in starting a single biologic DMARD, patients face more than $2,700 in copayments each year before receiving relief from catastrophic coverage. Results published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), show that during the initial phase of coverage, most people are expected to pay a striking 29.6% of total biologic drugs costs (just under one-third) out-of-pocket, creating an enormous financial burden for patients with chronic, rheumatic diseases such as rheumatoid arthritis (RA).
A new study has found a strong link between prolonged work at the World Trade Center (WTC) site following the terrorist attacks of September 11, 2001 and the development of various autoimmune diseases including arthritis and lupus.
A new study found that Black and Hispanic patients are less likely than Whites to receive proper care prior to diagnosis with end-stage renal disease due to lupus nephritis, especially in terms of vascular access placement.
A randomized controlled trial in patients 65 years of age and older shows that a “new and lighter treatment” plan was safer and more effective than conventional therapy in inducing remission in the systemic necrotizing vasculitides—a group of diseases that cause inflammation in various blood vessels
New research published in Arthritis & Rheumatology reports that osteoarthritis (OA) is more common in patients following anterior cruciate ligament reconstruction, commonly known as ACL surgery, than in those with uninjured knees
A new study by researchers from Brigham and Women’s Hospital in Boston, Massachusetts reveals that Asian and Hispanic patients with systemic lupus erythematosus (SLE) have lower mortality rates compared to Black, White, or Native Americans with the disease. Findings published in Arthritis & Rheumatology,a journal of the American College of Rheumatology (ACR), indicate that the risk for death among White patients is much lower than in Black and Native American SLE patients.
Novel research reveals that the risk of acute gout attacks is more than two times higher during the night or early morning hours than it is in the daytime. The study published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), confirms that nocturnal attacks persist even among those who did not consume alcohol and had a low amount of purine intake during the 24 hours prior to the gout attack.
Researchers from Denmark and the U.S. report that babies of women with rheumatoid arthritis (RA) or pre-clinical RA—the period prior to symptoms—are 1.5 times more likely to be born prematurely in Denmark. Findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), indicate that body measurements of the baby at birth were only slightly lower in children exposed to maternal or preclinical RA compared to those with no exposure to the disease. Paternal RA was not found to impact fetal growth or preterm birth risk.
Ankylosing spondylitis is a systemic disease that causes inflammation in the spinal joints and was thought to have affected members of the ancient Egyptian royal families. Now a new study published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), refutes that claim, finding instead a degenerative spinal condition called diffuse idiopathic skeletal hyperostosis (DISH) in royal Egyptian mummies from the 18th to early 20th Dynasties.
New research shows that patients with fibromyalgia have hypersensitivity to non-painful events based on images of the patients’ brains, which show reduced activation in primary sensory regions and increased activation in sensory integration areas. Findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), suggest that brain abnormalities in response to non-painful sensory stimulation may cause the increased unpleasantness that patients experience in response to daily visual, auditory and tactile stimulation.
A new study reveals that one in six patients with systemic lupus erythematosus (SLE) is readmitted to the hospital within 30 days of being discharged. Results published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), show that black and Hispanic SLE patients were more likely to be readmitted than white patients. Readmissions among patients insured by Medicare or Medicaid were also more likely compared to patients covered by private insurance.