British Journal of Clinical Pharmacology

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You selected: British Journal of Clinical Pharmacology

12:00 AM EST January 16, 2014

Does taking multiple medicines increase your risk of being admitted to hospital? Yes and No.

Patients with a single illness who take many drugs have an increased risk of being admitted to hospital, but for patients with multiple conditions, taking many medicines is now associated with a near-normal risk of admission. This is the key finding of work published in the British Journal of Clinical Pharmacology. Doctors call the situation where people take many drugs ‘polypharmacy’, a state of affairs that is becoming increasingly common in part because we have more elderly people and also a rising number of people are being diagnosed with multiple health conditions.

7:00 PM EST December 05, 2012

EPO Doping in Elite Cycling: No Evidence of Benefit, But High Risk of Harm

The drug erythropoietin, often called EPO, is banned from sports because it is believed to enhance an athlete’s performance and give people who use it an unfair advantage over unenhanced competitors. However a new systemic review of existing research, published in the British Journal of Clinical Pharmacology, reveals that there is no scientific evidence that it does enhance performance, but there is evidence that using it in sport could place a user’s health and life at risk.

7:00 PM EDT September 12, 2012

Antidepressants, Sleeping Pills and Anxiety Drugs May Increase Driving Risk

Drugs prescribed to treat anxiety, depression and insomnia may increase patients’ risk of being involved in motor vehicle accidents, according to a recent study, published in the British Journal of Clinical Pharmacology. Based on the findings, the researchers suggested doctors should consider advising patients not to drive while taking these drugs.

8:00 PM EDT March 21, 2012

Antidepressant Use During Pregnancy and High Blood Pressure

Use of selective serotonin re-uptake inhibitor (SSRI) antidepressants during pregnancy appears to be linked with increased risk of pregnancy induced high blood pressure (“hypertension”), but a causal link has not been established.

7:00 PM EST January 18, 2012

Nursing Home Residents with Dementia: Antidepressants Are Associated With Increased Risk of Falling

Nursing home residents with dementia who use average doses of selective serotonin reuptake inhibitors (SSRIs) are three times more likely to have an injurious fall than similar people who don’t use these drugs. The association can be seen in people who use low doses of SSRIs and the risk increases as people take higher doses. The results are published in the British Journal of Clinical Pharmacology.

7:00 PM EST November 22, 2011

Paracetamol: Repeated Ingestion of Slightly Too Much Can Be Fatal – Recognise and Treat Quickly

Repeatedly taking slightly too much paracetamol over time can cause a dangerous overdose that is difficult to spot, but puts the person at danger of dying. Patients may not come to hospital reporting the overdose, but because they feel unwell. This clinical situation needs to be recognized and treated rapidly because these patients are at even greater danger than people who take single overdoses.

12:00 AM EST November 15, 2011

New Hi-tech Survey Accelerates Collection of Vaccination Data and Adds to Evidence for Safety of 2009-10 Swine Flu Vaccination

New technology now makes it possible to collect ‘near real-time’ data about whether people are having any side effects from vaccination. By studying people who received the 2009-10 swine flu vaccination in Scotland, researchers showed that this rapid reporting can add another layer of safety to future vaccination campaigns. In addition, the data collected revealed no significant safety issues in patients exposed to the vaccine. The project’s report has just been published in the British Journal of Clinical Pharmacology.

May 19, 2011

Scottish Data Highlights Dangerous Practice in Paediatric Paracetamol Prescribing

Many of the prescriptions issued by GPs for paracetamol either give less than recommended doses to older children or exceed recommended doses in young children.

October 14, 2010

Study Warns That Over the Counter Weight Reducing Products Can Cause Harm and May Even Kill

A study of medical records in Hong Kong revealed 66 cases where people were suspected to have been poisoned by a “natural” slimming therapy. In eight cases the people became severely ill, and in one case the person died. The study is published today in the British Journal of Clinical Pharmacology.

January 21, 2010

Impact of ‘Get Randomised’ Campaign in Scotland

'Get Randomised' - a public campaign to highlight the importance of randomised clinical trials - boosted awareness and knowledge of clinical trials around Scotland, a new study has shown.

October 14, 2009

Don’t Block Folic Acid in Early Pregnancy: Medications That Block Folic Acid Are Associated With Increased Abnormalities

Using medication that reduces or blocks the actions of folic acid during the first trimester of pregnancy (weeks 1-12), increases the risk that the growing baby will develop abnormalities.

September 03, 2009

Rise In Weight-Loss Drugs Prescribed To Combat Childhood Obesity

Research news from the British Journal of Clinical Pharmacology