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Majority of stillbirth cases remain unexplained, suggesting post mortem investigation needs to be refined, GOSH research finds
Analysis by a Great Ormond Street Hospital (GOSH) led team looking at the effectiveness of different elements of the post mortem process shows that, despite full standard investigation, in the majority of cases of stillbirth the cause remains unknown. The papers highlight the need for further research to improve post mortem techniques to better detect a cause of death.
The findings, published in the Journal of the American Geriatrics Society, come from the first systematic review of studies focused on oral health and cognition.
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A new review indicates that antimicrobial therapy given before clinicians take transrectal ultrasound-guided prostate biopsies to diagnose prostate cancer may lead to lower rates of sepsis, a potentially life-threatening infection.
In a recent analysis of US data, one in seven colorectal patients was younger than 50 years old, the recommended age to begin screening. Younger patients were more likely to be diagnosed with advanced stage disease; however, they received more aggressive therapy and lived longer without a cancer recurrence, suggesting some compensation for their later diagnosis. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings raise questions concerning how younger adults’ risk of developing colorectal cancer should be assessed, and whether or not they should be screened.
A new analysis indicates that delirium commonly develops in the older patients who have undergone gastrointestinal surgery. Among 11 studies analyzed, the incidence of postoperative delirium ranged from 8.2 to 54.4 percent.
A new study indicates that transplant centers that receive low scores on performance evaluations tend to remove more patients from the transplant waiting list. According to US data from the Scientific Registry of Transplant Recipients on 315,796 candidates on the kidney transplant waiting list from 2007 to 2014, the rate of removal was approximately 60% higher for centers that received low performance evaluations compared with all other centers, even after adjusting for candidates’ demographic and clinical characteristics.
For patients undergoing urologic surgery, frailty may increase their risk of experiencing complications after surgery.
Socio-economic status may influence the use of health resources among children with epilepsy, even in a universal health insurance system.
A new report by a Task force of the American Society for Bone and Mineral Research provides guidance on the use of bisphosphonates, which are the most commonly used medications for osteoporosis.
A new study in rats may provide significant insights into the long-term impacts of over-consumption of sugary foods during adolescence.
In older adults, declining health is a major reason they stop driving. But when they stop driving, what impact does this have on their subsequent health and well-being?
Little is known about the long-term health of survivors of childhood cancers that affect vision, but two new studies provide valuable insights that could impact patient care and follow-up. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.
A new Cochrane Review published today shows that targeting exercises to muscles that support and control the spine offers another strategy to reduce pain and disability caused by lower back pain.
Factors in the blood from calorie-restricted rats can modify energy-producing mitochondria within the insulin-producing cells that regulate blood sugar levels, new research shows. This has a positive impact on glucose-stimulated insulin secretion and protects cells from fatty acid and glucose toxicity.
Using paroxetine—a medication prescribed to treat conditions including depression, obsessive-compulsive disorder, anxiety and posttraumatic stress disorder—during the first trimester of pregnancy may increase newborns’ risk of congenital malformations and cardiac malformations. That’s the conclusion of a recent analysis published in the British Journal of Clinical Pharmacology.
Investigators estimate that during 2012, there were more than 3.1 million emergency department visits for infectious diseases among elderly US adults.
The new Concise Guide to PHARMACOLOGY 2015/2016 provides a valuable and unique overview of the key properties of more than 1,700 human drug targets, focusing on those exploited currently in the clinic or with future therapeutic potential.
Patients who have undergone radical prostatectomy often have largely unrealistic expectations with regard to their postoperative sexual function, new research shows.
A new study reveals that drug shortages affecting emergency care have skyrocketed in the United States in recent years. While the prevalence of such shortages fell from 2002 to 2007; the number of shortages sharply increased by 373% (from 26 to 123) from 2008 to 2014.
New research indicates that asthma in many adolescents is not likely to involve inflammation of the airways and therefore should not be considered an allergic disease.
A new study shows that earlier initiation of sexual intercourse increases the odds of experiencing sexually transmitted infections (STIs). Also, if the age at the time of first sexual intercourse is during or near to an adolescent’s sexual maturation period, the likelihood of experiencing STIs increases.
While epilepsy and migraines in children and adolescents are closely related neurologic disorders, youth with epilepsy face a significantly higher risk of dying prematurely.