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October 03, 2016

Serious Liver-Related Condition on the Rise in the U.S.

A new analysis reveals that cirrhosis and acute on chronic liver failure (ACLF, a deterioration of liver function in patients with cirrhosis that results in the failure of one or more organs) represent a substantial and increasing health and economic burden in the United States.

October 03, 2016

Should Video Monitors Be Used to Detect Night-time Seizures in Patients with Epilepsy?

Following a sudden death at a residential care unit, the Dutch Health and Care Inspectorate advised to intensify the use of video monitoring at the unit. Researchers now report that such video monitoring can help detect seizures at night, but the costs are high.


September 28, 2016

Some Herbal and Dietary Supplements Can Be Toxic to the Liver

A new review based on a research symposium sponsored by the American Association for the Study of Liver Disease and the National Institutes of Health highlights the potentially damaging effects of herbal and dietary supplements (HDSs) on the liver.

September 27, 2016

Bioethicists Challenge Doctors’ Right to Refuse Care

In a recent article, the Editors-in-Chief of two leading ethics journals stress that there should be better protections for patients from doctors’ personal values as well as more severe restrictions on the right of clinicians to conscientious objection, particularly in relation to assisted dying. 

September 27, 2016

Study Reveals Tremendous Clinical and Economic Burden of Common Chronic Liver Disease

Non-alcoholic fatty liver disease (NAFLD), the most common liver disease worldwide, is increasing in prevalence and is currently estimated to affect approximately one-quarter of the general population. A new study published in the journal Hepatology reveals the clinical and economic burden of NAFLD in the United States and Europe. The findings will help clinicians and policy makers develop strategies to deal with this serious chronic disease.

12:00 AM EDT September 26, 2016

Expectations May Not Match Reality among Cancer Patients in Some Early Phase Clinical Trials

In a study of cancer patients considering whether they should participate in phase I clinical trials, a high percentage were willing to participate after discussions with clinical staff, but nearly half thought that their tumors would shrink, which is much higher than what is realistically achieved. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings demonstrate the challenges facing patients and healthcare professionals during their interactions in phase I studies.

September 21, 2016

Rare Genetic Condition May Provide Insights on Parkinson’s and other Late-Onset Diseases

A new article suggests that an enzyme deficiency seen in the lysosomal storage disorder Krabbe’s disease may point to new and contributing mechanisms underlying certain late-onset neurodegenerative diseases such as Parkinson’s disease.


September 19, 2016

Abaloparatide Benefits a Wide Range of Postmenopausal Women with Osteoporosis

A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide-SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with osteoporosis regardless of their baseline bone density, age, and previous history of fracture. 

September 19, 2016

Binge-Eating Disorder Linked to Other Health Conditions

Binge-eating disorder (BED) was linked with a broad range of other illnesses in a recent study, with the strongest associations related to the endocrine and circulatory systems. 

September 19, 2016

Cooking Fuels Contribute to Childhood Pneumonia in Developing Countries

Solid fuels used for cooking are the prevailing source of indoor pollution in developing countries. Now a worldwide ecological assessment has found that rates of pneumonia among young children in different countries are linked with the use of solid fuels. 

September 19, 2016

Diet and Exercise May Improve Physical Function and Quality of Life in Older Obese Adults

A recent review and analysis of published studies since 2005 found low-to-moderate evidence that dietary and exercise interventions can improve physical function and quality of life in older adults with obesity.

September 19, 2016

Film and Television Often Provide Misleading Information on Brain Death

Neurologists who examined how brain death and organ donation are portrayed in film and television found that only a small fraction of productions provide the public with a complete and accurate understanding of brain death. In addition, most productions do not provide professional discussions about organ donation.

September 19, 2016

People with Epilepsy Face Increased Risks of Discrimination and Other Negative Life Events

In a recent analysis, people with epilepsy were seven-fold more likely to have reported experiencing discrimination due to health problems than the general population. This risk was greater than other chronic health problems such as diabetes, asthma and migraines. 

September 19, 2016

Stem Cell–Based Screening Methods May Predict Heart-Related Side Effects of Drugs

Coaxing stem cells from patients to become heart cells may help clinicians personalize drug treatments and prevent heart-related toxicity. A new review looks at the potential of this strategy, noting that these so-called human pluripotent stem cell-derived cardiomyocytes may be used in screening methods to determine which patients are at risk of experiencing heart-damaging effects of chemotherapy agents and other drugs.

September 19, 2016

Study Estimates ADHD Symptom Persistence into Adulthood

Sixty percent of children with ADHD in a recent study demonstrated persistence of symptoms into their mid-20’s, and 41 percent had both symptoms and impairment as young adults.

September 19, 2016

Study Reveals Scope and Characteristics of Adverse Drug Reactions in the General Population

In a study of 1000 adult patients with unplanned admission to a tertiary hospital in Singapore, the prevalence of adverse drug reactions (ADRs) at the time of admission was 12.4 percent, and the prevalence of ADRs causing admission to the hospital was 8.1 percent. 

September 15, 2016

Research provides clues to how zika virus breaches the placental barrier

New research reveals that in pregnant women, Zika virus infection damages certain cells that affect placental formation and function. Furthermore, herpes simplex virus-2 (HSV-2) infection augments placental sensitivity to Zika virus by enhancing the expression of receptors that allow Zika virus to enter cells.

September 14, 2016

Cochrane Review: Conclusions about the effects of electronic cigarettes remain the same

An updated Cochrane Review published today provides an independent, rigorous assessment of the best available evidence to date about electronic cigarettes for quitting smoking.

12:00 AM EDT September 12, 2016

Many Adolescent Girls with Leukemia Are Not Being Screened for Pregnancy Before Beginning Chemotherapy

A new study indicates that adolescent females with acute leukemia have low rates of pregnancy screening prior to receiving chemotherapy that can cause birth defects. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

September 12, 2016

Many alcohol-related injuries occur at home

Of all alcohol-related injuries in various public hospital emergency departments in Queensland, Australia, more occurred at home than at licensed premises.