Medicine & Healthcare

A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX). Results of the 12-month interim analysis of the efficacy of tofacitinib appear in Arthritis & Rheumatism, a journal published by Wiley on behalf of the American College of Rheumatology (ACR).

Published by Wiley, this new 10-volume set captures every aspect of the interdisciplinary nature of magnetic resonance and provides the most complete and up-to-date source in the field.

A new study published in The Journal of Sexual Medicine reveals that within a nationally representative study of American men and women, sex was rated as highly arousing and pleasurable whether or not condoms and/or lubricants were used. Condoms and lubricants are commonly used by both women and men when they have sex.

First pregnancies complicated by postpartum haemorrhage (PPH) have no detrimental effect on future fertility but women who have caesarean sections at the time of PPH are less likely to conceive again, finds a new study published today (23 January) in BJOG: An International Journal of Obstetrics and Gynaecology.

Over 500 billion cells in our bodies will be replaced daily, yet natural selection has enabled us to develop defenses against the cellular mutations which could cause cancer. It is this relationship between evolution and the body’s fight against cancer which is explored in a new special issue of the Open Access journal Evolutionary Applications.

According to results of a new study by researchers at the University of Utah, military personnel experience increased risk of suicidal thoughts or actions if they were the victims of physical or violent sexual assault as adults. In contrast, undergraduate students experience increased risk of suicidal thoughts or actions if they were the victims of unwanted sexual experiences as children or adults.

Carbon nanotubes resemble asbestos fibers in their form. Unfortunately, long, pure nanotubes also seem to have asbestos-like pathogenicity. In the journal Angewandte Chemie, a European research team has now reported that chemical modifications, for example with tri(ethylene glycol), can alleviate this problem if the modification makes their surface more water-friendly and reduces the effective length of the tubes.

How can pharmaceuticals be safely carried through the acidic environment of the stomach and into the intestines? A team of Canadian and Australian researchers has developed a novel nanotransporter that consists of porous particles of silicon dioxide stabilized with a whey protein. In acidic environments the protein forms a gel that closes off the pores; at higher pH values, the pores are opened.

Smoking not only causes bladder cancer—it also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study also found that a panel of bladder cancer markers can predict which particular cases are at the highest risk for a fatal outcome.

Herbal and complementary medicines could be recommended as an alternative to hormone replacement therapy (HRT) for treating postmenopausal symptoms says a new review published today in The Obstetrician and Gynaecologist (TOG).

Women should wait at least 12 months before trying for a baby following weight loss surgery and need further advice and information on reproductive issues, suggests a new evidence-based literature review published today (11/01/13) in The Obstetrician & Gynaecologist (TOG).

Women with pre-eclampsia are at a higher risk of complications following delivery and should continue to be monitored for up to 72 hours, suggests a new review published today (11/01/13) in The Obstetrician and Gynaecologist (TOG).

A new study, funded in part by the National Institutes of Health (NIH) and Health Resources and Services Administration, and published in the January 2013 issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD), found that the non-use of donor livers climbed through 2010 due to a worsening of donor liver quality, primarily from donation following cardiac death. Diabetes, donor age, and body mass index (BMI) were also linked to a decrease in use of organs.

New research reveals that a significant number of adolescents lose their protection from hepatitis B virus (HBV) infection, despite having received a complete vaccination series as infants. Results in the January 2013 issue of Hepatology, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases, suggest teens with high-risk mothers (those positive for HBeAg) and teens whose immune system fails to remember a previous viral exposure (immunological memory) are behind HBV reinfection.

Written and edited by today's most-recognized interventional cardiology thought leaders, this guide for interventional cardiologists focuses on key procedures and techniques and provides "tips and tricks" gathered from the personal experience of over fifty international experts.

Small Animal Soft Tissue Surgery offers the state-of-the-art, comprehensive resource on the surgical treatment of diseases and syndromes in small animal patients, with detailed, well-illustrated descriptions of surgical procedures.

New research reveals a shared genetic susceptibility to epilepsy and migraine. Findings published in Epilepsia, a journal of the International League Against Epilepsy (ILAE), indicate that having a strong family history of seizure disorders increases the chance of having migraine with aura (MA).

New research into the association between alcohol marketing and binge drinking by youth has explored the impact of drinker identity and brand allegiance on underage drinkers. The research, published in Alcoholism: Clinical & Experimental Research, are the results of a national U.S survey which explored the perceptions of over 1,700 15-to-20-year-olds and examined how many thought of themselves as a drinker or had a favorite brand of alcohol, perceptions which are actively cultivated by alcohol marketers.

10 years of study into the ability of Coca-Cola to dissolve stomach blockages reveals the fizzy drink to be successful in over 90% of cases. The research, published in Alimentary Pharmacology & Therapeutics, looked at 24 papers including 46 patients and found that in 91.3% of cases stomach blockages were cleared, while only 4 patients were required to follow this with surgery.