Explore Topics
Gastrointestinal and Liver Physiology
Motility
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Historical Perspectives
- Gastrointestinal physiology, 1895-1975: motility
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Musculature
- Structure of intestinal musculature
- Distribution and exchange of electrolytes in gastrointestinal muscle cells
- Electrophysiology of dissociated gastrointestinal muscle cells
- Electrophysiology of the gastric musculature
- Electrophysiology of the intestinal musculature
- Electrophysiology of colonic smooth muscle
- Mechanical properties of gastrointestinal smooth muscle
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Neurobiology
- Enteric neurons in culture
- Interstitial cells of Cajal
- Identification of transmitters of functionally defined enteric neurons
- Neurotransmitter release in the enteric nervous system
- Neuromuscular transmission in the gastrointestinal tract
- Electrical and synaptic behavior of enteric neurons
- Physiology of prevertebral ganglia in mammals with special reference to inferior mesenteric ganglion
- Sensory afferents from the gastrointestinal tract
- Control centers in the central nervous system for regulating gastrointestinal motility
- Central nervous system mechanisms in deglutition and emesis
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Pharmacology
- Pharmacology of drugs acting on gastrointestinal motility
- Pharmacology of neuroendocrine peptides
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Motor Function
- In vivo myoelectric activity: methods, analysis, and interpretation
- Esophageal motility
- Determinants of gastric emptying and transit in the small intestine
- Colonic motility
- Villous motility
- Sphincteric function
- Motor function of anorectum and pelvic floor musculature
- Motility of the biliary system
- Pharmacology of biliary tract
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Abnormal Motility
- Parasite infections and gastrointestinal motility
- Alterations of small intestine motility by bacteria and their enterotoxins
- Motor and myoelectric activity associated with vomiting, regurgitation, and nausea
- Adaptation to surgical perturbations
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Comparative Physiology
- Gastrointestinal motor functions in ruminants
- Avian gastrointestinal motor function
Circulation
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Structure
- Histoanatomy and ultrastructure of vasculature of alimentary tract
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Hemodynamics
- Gastrointestinal blood flow-measuring techniques
- Physiology of gastric circulation
- Microcirculation of the intestinal mucosa
- Gastrointestinal circulation and motor function
- Hepatic circulation
- Circulation of the pancreas and salivary glands
- Neonatal intestinal circulation
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Neurobiology
- Electrophysiological and neuromuscular relationships in extramural blood vessels
- Neuromuscular transmission in intramural blood vessels
- Neurohormonal control of gastrointestinal blood flow
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Abnormal Circulation
- Pathophysiology of gastrointestinal circulation
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Lymphatic Circulation
- Gastrointestinal lymphatics
Neural and Endocrine Biology
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Properties of Gut Peptides
- Molecular biology of gut peptides
- Sequences of natural gut peptides, related peptides, and their precursors
- Posttranslational processing of gut peptides
- Endocrine cells of the gut
- Structure and neurochemical organization of the enteric nervous system
- Distribution of gut peptides
- Identification of physiological function of gut peptides
- Comparative neuroendocrinology of gut peptides
- Receptors for gut peptides and other secretagogues on pancreatic acinar cells
- Gastric mucosal receptors
- Peptide receptors in intestinal epithelium
- Liver receptors for regulatory peptides
- Receptors for gut peptides on smooth muscle cells of the gut
- Trophic effects of gut peptides
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Structure and Function of Gut Peptides
- Gastrin
- Cholecystokinin
- Secretin
- Gastric inhibitory polypeptide
- Somatostatin
- Gut glucagon
- Pancreatic polypeptide family: pancreatic polypeptide, neuropeptide Y, and peptide YY
- Motilin
- Neurotensin
- Bombesin-like peptides
- Vasoactive intestinal peptide
- Opioid peptides of the gut
- Gut tachykinins
- Newly discovered gut peptides
Salivary, Gastric, Pancreatic, and Hepatobiliary Secretion
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Salivary
- Fluid and electrolyte secretion by salivary glands
- Electrophysiology of salivary and pancreatic acinar cells
- Calcium signaling system in salivary glands
- Cellular regulation of amylase secretion by the parotid gland
- Salivary mucin secretion
- Functional differentiation of salivary glands
- Secretory membranes and the exocrine storage compartment
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Stomach
- Neural and hormonal control of gastric secretion
- Inhibition of gastric acid secretion
- Electrophysiology of gastric ion transport
- Cell biology of hydrochloric acid secretion
- Biochemistry of gastric acid secretion: H+ K+-ATPase
- Intracellular activation events for parietal cell hydrochloric acid secretion
- Cellular basis of pepsinogen secretion
- Gastric mucosal barrier
- Secretion of bicarbonate by gastric and duodenal mucosa
- Immunological probes of gastrointestinal secretion
- Functional development of stomach
- Gastrointestinal mucus
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Pancreas
- Pancreatic secretion of electrolytes and water
- Cellular regulation of pancreatic secretion
- Signaling transduction in hormone- and neurotransmitter-induced enzyme secretion from the exocrine pancreas
- Regulation of digestive reactions by the pancreas
- Cellular compartmentation and protein processing in the exocrine pancreas
- Selective regulation of gene expression in the exocrine pancreas
- Long-term regulation of pancreatic function studied in vitro
- Structural and secretory polarity in the pancreatic acinar cell
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Hepatobiliary
- Overview of bile secretion
- Enterohepatic circulation of bile acids
- Cellular mechanisms of hepatic fluid and electrolyte transport
- Physical chemistry of bile
- Pathways and function of biliary protein secretion
- Hepatocyte lysosomes in intracellular digestion and biliary secretion
- Hepatic transport of organic solutes
- Transport and metabolism in the hepatobiliary system
Intestinal Absorption and Secretion
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Basic Principles of Structure and Function
- Principles of membrane transport
- Biology of sodium-absorbing epithelial cells: dawning of a new era
- Functional morphology of epithelium of the small intestine
- Functional morphology of the large intestine
- Mechanism of fluid transport by epithelia
- Enterocyte cytoskeleton: its structure and function
- Use of cultured cell lines in studies of intestinal cell differentiation and function
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Intestinal Transport of Inorganic Ions
- Ion transport across the large intestine
- Comparative physiology of colonic electrolyte transport
- Ion transport across mammalian small intestine
- Salt and water transport by gallbladder epithelium
- Inorganic phosphate absorption in small intestine
- Transport of calcium
- Iron absorption
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Intestinal Transport of Organic Compounds
- Transport of weak electrolytes
- Intestinal transport of bile acids
- Molecular biology of Na-/glucose symport
- Dietary protein processing: intraluminal and enterocyte surface events
- Intestinal transport of water-soluble vitamins
- Gastric intrinsic factor and cobalamin absorption
- Immunoglobulin A secretion
- Luminal events in gastrointestinal lipid digestion
- Enterocyte lipid absorption and secretion
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Regulation of Intestinal Ion Transport
- Neurohormonal control of fluid and electrolyte transport in intestinal mucosa
- Immunophysiology of intestinal electrolyte transport
