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Neurophysiology

Cellular Biology of Neurons

  • General Perspectives

    • Overview
  • Morphology of Neurons and Neuroglia

    • General morphology of neurons and neuroglia
  • Excitation and Conduction

    • Core conductor theory and cable properties of neurons
    • Ionic basis of resting and action potentials
    • Structural and metabolic processes directly related to action potential propagation
    • Physical principles and formalisms of electrical excitability
    • Activation in striated muscle
  • Junctional Transmission

    • Structure of the synapse
    • Junctional transmission I. Postsynaptic mechanisms
    • Junctional transmission II. Presynaptic mechanisms
    • Electrical transmission: a functional analysis and comparison to chemical transmission
    • Junctional transmission in smooth muscle and the autonomic nervous system
    • Biochemistry and physiology of cholinergic transmission
    • Biochemical aspects of neurotransmitter receptors
    • Cellular aspects of catecholaminergic neurons
    • Biochemistry and physiology of serotonergic transmission
    • Biochemistry and physiology of amino acid transmitters
    • Cellular biology of the neurosecretory neuron
    • Axonal transport: the intracellular traffic of the neuron
  • Cellular Interactions

    • Cell culture in neurobiology
    • Trophic interactions of neurons
    • Specificity of neurons and their interconnections
    • Glial cells
  • Systems of Neurons

    • Spinal neurons and synapses
    • Olfactory bulb: a simple system in the mammalian brain
    • Physiology of supraspinal neurons in mammals
  • Neurons and Invertebrate Behavior

    • Organization of invertebrate motor systems
    • Principles in the organization of invertebrate sensory systems
    • Neuronal plasticity and the modification of behavior

Motor Control

  • Historical Perspectives

    • Comments on history of motor control
  • Bones, Muscles, and Transmitters

    • Mechanics of skeleton and tendons
    • Muscle, the motor
    • Transmitters in motor systems
    • Motor prostheses
  • Reflexes, Neural Organization, and Control Systems

    • Muscle spindles: their messages and their fusimotor supply
    • Limitations of somatosensory feedback in control of posture and movement
    • Neural control of muscle length and tension
    • Tremor and clonus
    • Motor units: anatomy, physiology, and functional organization
    • Functional organization of motoneuron pool and its inputs
    • Integration in spinal neuronal systems
  • Descending Control Pathways

    • Anatomy of the descending pathways
    • Vestibulospinal and reticulospinal systems
    • Pyramidal tract
  • Cerebellum and Basal Ganglia

    • Cerebellar afferent systems
    • Electrophysiology of the cerebellar networks
    • Cerebellar control of posture and movement
    • Anatomy of the corpus striatum and brain stem integrating systems
    • Electrophysiology of the corpus striatum and brain stem integrating systems
    • Motor functions of the basal ganglia
  • Cerebral Control Mechanisms

    • Internal organization of the motor cortex for input-output arrangements
    • Role of motor cortex in voluntary movements in primates
    • Organization of secondary motor areas of cerebral cortex
    • Prefrontal cortex in motor control
  • Rhythmical Movements and their Voluntary Engagement

    • Control of locomotion in bipeds, tetrapods, and fish
    • Neural mechanisms of mandibular control: mastication and voluntary biting
  • Visuomotor Control

    • Control of eye movements
    • Eye-head coordination
  • Behavioral Motor Performance

    • Human manual control
    • Behavioral analysis of movement
    • Corollary discharges: motor commands and perception
    • Perceptual structures and distributed motor control

Sensory Processes

  • Historical Perspectives

    • Sensory research in historical perspective: some philosophical foundations of perception
  • Assessing the Physical Environment

    • Perception
    • Detection and discrimination of environmental change
    • Sensory function in animals
  • Structural Organization of Vertebrate Sensory Systems

    • Organization of the thalamocortical complex and its relation to sensory processes
    • Brain stem reticular core and sensory function
  • Vision

    • Beginnings of visual perception: the retinal image and its initial encoding
    • Vertebrate retina
    • Processing of visual information within the retinostriate system
    • Neural mechanisms of color vision
    • Superior colliculus and visual function
    • Postnatal development of function in the mammalian visual system
  • Hearing

    • Auditory perception
    • Peripheral mechanisms of hearing
    • Peripheral neural processing of auditory information
    • Central neural mechanisms of hearing
  • Somatic Sensation

    • Sense of touch: performance and peripheral neural processes
    • Central nervous mechanisms in mechanoreceptive sensibility
    • Thermal sensibility
    • Pain and nociception
  • The Body in Space

    • Vestibular system
    • Perception of the body in space: mechanisms
  • The Chemical Senses

    • Taste and olfaction: sensory discrimination
    • Central neural mechanisms of taste
  • The Cerebral Cortex and Perceptual Processes

    • Hemispheric specialization

Intrinsic Regulatory Systems of the Brain

  • Molecular Mechanisms of Interneuronal Regulation

    • Mechanisms of transmitter action in the vertebrate central nervous system
    • Mechanisms of autonomic integration
  • Specific Integrative Regulatory Systems

    • Catecholaminergic brain stem regulatory systems
    • Specific systems of the reticular core: serotonin
    • Histaminergic transmission in the brain
    • Organization of mammalian neuroendocrine system
  • Central Integrative Systems

    • Central nervous system control of nutrient homeostasis
    • Hypothalamohypophysiotropic peptide systems
    • Neurophysiology of breathing in mammals
    • Neurogenic control of the vascular system: focus on cerebral circulation
    • Central control of nociception
    • Reward, motivation, cognition: psychobiology of mesotelencephalic dopamine systems
    • Brain monoamines, homeostasis, and adaptive behavior
    • Neuronal basis of behavioral state control

Higher Functions of the Brain

  • General Perspectives

    • Neuroscience and higher brain function: from myth to public responsibility
  • Learning and Memory in Nonmammalian and Simple Systems

    • Cell biological studies of learning in simple vertebrate and invertebrate systems
    • Plasticity in adult avian central nervous system: possible relation between hormones, learning, and brain repair
  • Biology of Learning and Memory in Animals

    • Neurogenetics and behavior related to higher brain functions
    • Mechanisms of learning in complex neural systems
    • Diffuse cortical projection systems: anatomical organization and role in cortical function
    • Memory: anatomical organization of candidate brain regions
    • Memory: neural organization and behavior
    • Circuitry of primate prefontal cortex and regulation of behavior by representational memory
  • Mechanisms of Emotion and Attention

    • Emotion
    • Attention: Behavior and neural mechanisms
  • Mechanisms of Perception

    • Inferior parietal lobule function in spatial perception and visuomotor integration
    • Electrophysiology of cognition
    • Preattentive human vision: link between neurophysiology and psychophysics
  • Theoretical Model of Higher Brain Functions

    • Artificial intelligence: computational approach to vision and motor control
  • Focal Aspects of Human Higher Brain Functions

    • Circulatory and metabolic correlates of brain function in normal humans
    • Language in humans and animals: contribution of brain stimulation and recording
    • Cerebral lateralization and specialization in human central nervous system
    • Abnormalities of motor behavior after cortical lesions in humans
  • Human Disease and Higher Brain Functions

    • Epilepsy: insights into higher brain functions in humans
    • Schizophrenia: nature of the disease process and its biological correlates
    • Neural correlates of cognitive impairment in Alzheimer's disease