Tinkering: The Microevolution of Development, No. 284
This book explores both theoretical and practical issues of tinkering. It features a wide range of perspectives to address several fundamental questions. How does tinkering occur developmentally, and how is it manifested phenotypically? Are the developmental mechanisms by which tinkering occur different from those that underlie larger evolutionary changes? What are the developmental constraints on tinkering? And how do we test hypotheses about microevolutionary shifts in development from the fossil record?
With contributions from experts in a range of fields, this fascinating book makes exciting reading for anyone studying evolution, developmental biology or genetics.
Editors: Gregory Bock (Organizer) and Jamie Goode.
This symposium is based on a proposal made by Brian Hall.
Daniel E. Lieberman The evolutionary developmental biology of tinkering: an introduction to the challenge.
Manfred D. Laubichler Tinkering: a conceptual and historical
Rudolf A. Raff and Elizabeth C. Raff Tinkering: new embryos from
old-rapidly and cheaply.
James M. Cheverud The relationship between development and
evolution through heritable variation.
Adam S. Wilkins Genetic networks as transmitting and amplifying
devices for natural genetic tinkering.
Paul M. Brakefield Butterfly eyespot patterns and how
evolutionary tinkering yields diversity.
General discussion I.
Günter P. Wagner and Anna Marie Pyle Tinkering with
transcription factor proteins: the role of transcription factor
adaptation in developmental evolution.
Denis Duboule, Basile Tarchini, Jozsef Zàkàny and
Marie Kmita Tinkering with constraints in the evolution of the
vertebrate limb anterior-posterior polarity.
Irma Thesleff, Elina Järvinen and Marika Suomalainen
Affecting tooth morphology and renewal by fine-tuning the signals
mediating cell and tissue interactions.
General discussion II.
Benedikt Hallgrimsson, Daniel E. Lieberman, Nathan M. Young,
Trish Parsons and Steven Wat Evolution of covariance in the
David L. Stern The developmental genetics of
Jukka Jernvall and Isaac Salazar-Ciudad The economy of tinkering
Michael A. Bell, Kaitlyn E. Ellis and Howard I. Sirotkin Pelvic skeleton reduction and Pitx1 expression in threespine stickleback populations.
Michael I. Coates, Marcello Ruta and Peter J. Wagner Using
patterns of fin and limb phylogeny to test
Rebecca R. Ackermann Craniofacial variation and developmental
divergence in primate and human evolution.
Chair: DANIEL LIEBERMAN, Harvard University, Cambridge, USA