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Vascular Hemodynamics: Bioengineering and Clinical Perspectives

ISBN: 978-0-470-08947-7
354 pages
October 2008, Wiley-Blackwell
Vascular Hemodynamics: Bioengineering and Clinical Perspectives (0470089474) cover image

Description

The only complete work on vascular hemodynamics

Recently, vascular hemodynamics has undergone major advances, resulting from increasingly sophisticated imaging, computational, and clinical research methodologies. The effects of these advances are likely to be profound at both the scientific and clinical levels. Now, Vascular Hemodynamics provides a self-contained treatment of this rapidly advancing topic as it relates to vascular disease and related pathologies in the human body.

Utilizing a multidisciplinary approach encompassing engineering, vascular biology, vascular imaging, and clinical practice, the book provides a survey of the basic science and clinical research in hemodynamics of the vasculature. The topics presented involve sophisticated modeling, imaging, and measurement techniques. The text emphasizes both the technical and clinical aspects of the field.

Additionally, Vascular Hemodynamics:
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Includes a wide variety of models of vascular pathology, including physical models, finite-element models, linear-system models, transmission-line models, and dye-dilution models
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Discusses diverse pathologies of the large vessels, the microvasculature, and the systematic vasculature
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Brings together a range of imaging modalities related to hemodynamics
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Includes both introductory-level and research-oriented material on each topic

Vascular Hemodynamics is the only single-text treatment of this important topic, making it a vital reference for researchers and students of bioengineering, radiology, vascular surgery, neurology, nephrology, cardiology, and oncology.
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Table of Contents

Preface vii

Contributors ix

1. Modeling the Vascular System and Its Capillary Networks 1
Thomas H. Dawson

2. Wall Shear Stress in the Arterial System In Vivo: Assessment, Results, and Comparison with Theory 37
Robert S. Reneman, Theo Arts, and Arnold P. G. Hoeks

3. Relating Cerebral Aneurysm Hemodynamics and Clinical Events 63
Juan R. Cebral and Christopher M. Putman

4. Prognostic Significance of Aortic Pulse-Wave Velocity 85
Tine Willum Hansen, Jørgen Jeppesen, and Christian Torp-Pedersen

5. Closed-Loop Modeling of the Circulatory System 94
Carol L. Lucas, Randal Cole, and Ajit Yoganathan

6. Artery Wall Mechanics Determined by Ultrasound 133
Arnold P. G. Hoeks, Evelien Hermeling, and Robert S. Reneman

7. Plaque Mechanics 157
Zhi-Yong Li

8. The Pressure Gradient at Arterial Stenoses: Towards a Noninvasive Measurement 183
Peter J. Yim

9. Measurement of Blood Flow with Phase Constrast Magnetic Resonance Imaging 213
Reza Nezafat and Richard B. Thompson

10. Measuring Cerebral Perfusion Using Magnetic Resonance Imaging 245
Fernando Calamante

11. Cerebral Perfusion Computed Tomography in Stroke 273
Max Wintermark

12. Cerebrovascular Reactivity Changes in Symptomatic Carotid Stenosis 285
Natan M. Bornstein and Alexander Y. Gur

13. Essential Hypertension, Cerebrovascular Reactivity, and Risk of Stroke 299
Cristina Sierra

Index 315

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Author Information

Peter J. Yim, PhD, is Assistant Professor in the Department of Radiology at the UMDNJ – Robert Wood Johnson Medical School in New Brunswick, New Jersey. He is a recognized leader in the field of hemodynamic modeling and imaging of the vascular system, with awards in these areas from the Radiological Society of North America, the National Institutes of Health, and the SPIE.

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Reviews

“This is the only complete book on this topic, providing readers with a clear and comprehensive understanding of the fundamentals of and recent advances in the field of hemodynamics as it relates to vascular disease states in the human body.” (Doody's Reviews, March 2009)
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