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Strategies for Reducing Drug and Chemical Residues in Food Animals: International Approaches to Residue Avoidance, Management, and Testing

ISBN: 978-0-470-24752-5
344 pages
September 2014
Strategies for Reducing Drug and Chemical Residues in Food Animals: International Approaches to Residue Avoidance, Management, and Testing  (0470247525) cover image

Highlighting international approaches; the book details strategies to minimize contamination, residue monitoring programs, and classes of drugs and chemicals that pose contaminant risk in livestock.

• Focuses attention on drug and chemical residues in edible animal products
• Covers novel computational, statistical, and mathematical strategies for dealing with chemical exposures in food animals
• Details major drug classes used in food animal production and their residue risks
• Highlights efforts at harmonizing and the differences among areas like US, EU, Canada, Australia, South America, China, and Asia, where the issue of chemical exposures has significant impact on livestock products
• Ties veterinary clinical practice and the use of these drugs in food animals with regulatory standards and mitigation practices
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Preface

Chapter 1. Importance of Veterinary Drug Residues
Ronald Baynes and Jim E. Riviere

Chapter 2. Pharmacokinetic Principles for Understanding Drug Depletion as a Basis for Determination of Withdrawal Periods for Animal Drugs
Sanja Modric

Chapter 3. Evaluation of Drug Residue Depletion in the Edible Products of Food‑Producing Animals for Establishing Withdrawal Periods and Milk Discard Times
Dong Yan

Chapter 4. Establishing MRLs in Europe
Kornelia Grein and Isaura Duarte

Chapter 5. Methods to derive withdrawal periods in the European Union
G. Johan Schefferlie and Stefan Scheid

Chapter 6. Population pharmacokinetic modeling to predict withdrawal times
Sharon E. Mason

Chapter 7. Physiologic-based Pharmacokinetic Modeling
Jennifer Buur

Chapter 8. Residue avoidance in Beef Cattle production systems
Virginia Fajit and Dee Griffin

Chapter 9. Residue avoidance in Dairy Cattle production systems
Geof Smith

Chapter 10. Residue avoidance in Aquaculture production systems
Renate Reimschuessel

Chapter 11. Residue avoidance in Small Ruminant production systems
Kevin Anderson

Chapter 12. Residue avoidance in swine production systems
Ronald Baynes and Glen Almond

Chapter 13. Confirmatory methods of livestock commodities
Mary Carson and Hui Li

Chapter 14. The Food Animal Residue Avoidance Databank: An example of Risk Management of Veterinary Drug Residues
Tom Vickroy, Ronald Baynes, Lisa Tell, and Jim E. Riviere

Chapter 15. Risk Management of Chemical Contaminants in Livestock
Ronald Baynes and Jim E. Riviere

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Ronald Baynes is a Professor of Pharmacology and Director of the Center of Chemical Toxicology Research and Pharmacokinetics at the College of Veterinary Medicine at North Carolina State University and Fellow, American Academy of Veterinary Pharmacology and Therapeutics He has consulted for the National Institute of Environmental Health Sciences, the US Environmental and Protection Agency, and National Institute of Occupational Safety and Health on chemical exposure-related topics.


Jim Riviere
 is The MacDonald Chair in Veterinary Medicine and University Distinguished Professor at Kansas State University. He is an elected member of the Institute of Medicine of the National Academies, serves on its Food and Nutrition Board, and is a fellow of the Academy of Toxicological Sciences.

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