Statistics: A Biomedical IntroductionISBN: 9780470251614
482 pages
November 2007

The Wiley Classics Library consists of selected books that have become recognized classics in their respective fields. With these new unabridged and inexpensive editions, Wiley hopes to extend the life of these important works by making them available to future generations of mathematicians and scientists.
Currently available in the Series:
 T. W. Anderson The Statistical Analysis of Time Series
 T. S. Arthanari & Yadolah Dodge Mathematical Programming in Statistics
 Emil Artin Geometric Algebra
 Norman T. J. Bailey The Elements of Stochastic Processeswith Applications to the Natural Sciences
 Robert G. Bartle The Elements of Integration and Lebesgue Measure
 George E. P. Box & Norman R. Draper Evolutionary Operation: A Statistical Method for Process Improvement
 George E. P. Box & George C. Tiao Bayesian Inference in Statistical Analysis
 R. W. Carter Finite Groups of Lie Type: Conjugacy Classes and Complex Characters
 R. W. Carter Simple Groups of Lie Type
 William G. Cochran & Gertrude M. Cox Experimental Designs, Second Edition
 Richard Courant Differential and Integral Calculus, Volume I
 Richard Courant Differential and Integral Calculus, Volume II
 Richard Courant & D. Hilbert Methods of Mathematical Physics, Volume I
 Richard Courant & D. Hilbert Methods of Mathematical Physics, Volume II
 D. R. Cox Planning of Experiments
 Harold S. M. Coxeter Introduction to Geometry, Second Edition
 Charles W. Curtis & Irving Reiner Representation Theory of Finite Groups andAssociative Algebras
 Charles W. Curtis & Irving Reiner Methods of Representation Theory with Applications to Finite Groups and Orders, Volume I
 Charles W. Curtis & Irving Reiner Methods of Representation Theory with Applications to Finite Groups and Orders, Volume II
 Cuthbert Daniel & Fred S. Wood Fitting Equations to Data: Computer Analysis of Multifactor Data, Second Edition
 Bruno de Finetti Theory of Probability, Volume I
 Bruno de Finetti Theory of Probability, Volume II
 Morris H. DeGroot Optimal Statistical Decisions
 W. Edwards Deming Sample Design in Business Research
 Amos de Shalit & Herman Feshbach Theoretical Nuclear Physics, Volume 1—Nuclear Structure
 Harold F. Dodge & Harry G. Romig Sampling Inspection Tables: Single and Double Sampling
 J. L. Doob Stochastic Processes
CHAPTER 1: Introduction 1
CHAPTER 2: Elementary Rules of Probability 13
CHAPTER 3: Populations, Samples, and the Distribution of the Sample Mean 37
1. Populations and Distributions 38
2. Sampling from Finite Populations 64
3. The Distribution of the Sample Mean 72
CHAPTER 4: Analysis of Matched Pairs Using Sample Means 85
1. A Confidence Interval for the Treatment Effect 86
2. A Hypothesis Test for the Treatment Effect 96
3. Determining the Sample Size 102
CHAPTER 5: Analysis of the TwoSample Location Problem Using Sample Means 109
1. A Confidence Interval for the Difference Between the Population Means 110
2. A Hypothesis Test for the Difference Between the Population Means 116
3. Determining Sample Sizes 119
4. Testing the Assumption of Equal Population Variances 122
CHAPTER 6: Surveys and Experiments in Medical Research 131
Application of Statistics in Laboratory and Clinical Studies 131
Randomized Clinical Experiments 134
Ethics and Statistical Aspects of the Clinical Trial 137
Retrospective Studies, Prospective Studies, and Randomized Clinical Experiments 140
CHAPTER 7: Statistical Inference for Dichotomous Variables 149
A Confidence Interval for a Success Probability p 150
Hypothesis Tests for a Success Probability p 156
CHAPTER 8: Comparing Two Success Probabilities 173
A Confidence Interval for the Difference Between the Success Probabilities 174
A Hypothesis Test for the Difference Between the Success probabilities 178
CHAPTER 9: ChiSquared Tests 195
The ChiSquared Test for k Probabilities (Goodness of Fit) 196
r x k Tables: ChiSquared Tests of Homogeneity and Independence 201
A Test for Trend in Proportions 211
CHAPTER 10: Analysis of & Sample Problems 225
The Completely Randomized Experiment 226
The Randomized Blocks Experiment 241
CHAPTER 11: Linear Regression and Correlation 261
1. Linear Regression 262
2. Correlation 281
3. Rank Correlation 292
CHAPTER 12: Analysis of Matched Pairs Using Ranks 309
1. The Wilcoxon Signed Rank Test 310
2. A Nonparametric Confidence Interval Based on the Signed Rank Test 317
CHAPTER 13: Analysis of the TwoSample Location Problem Using Ranks 327
1. The Wilcoxon TwoSample Rank Sum Test 328
2. A Nonparametric Confidence Interval Based on the Rank Sum Test 333
CHAPTER 14: Methods for Censored Data 341
APPENDIX A: Glossary 361
APPENDIX B: Answers to Selected Questions and Solutions to Selected Problems 375
APPENDIX C: Mathematical and Statistical Tables 407
INDEX 451