Phycotoxins: Chemistry and Biochemistry
February 2008, Wiley-Blackwell
An alphabetical listing of toxins presented includes:
Azaspiracids; Brevetoxins; Cyanobacterial toxins; Domoic acid;
Gambierols; Gymnodimines, prorocentrolides, spirolides, pinnatoxins
and cyclic imines in general; Maitotoxin; Okadaic acid and
dinophysistoxins; Palytoxins and ostreocins; Pectenotoxins;
Polycavernosides; and Yessotoxins. In addition, several mechanistic
aspects of newer or emerging toxins are covered such as amphidinols
or gymnocine. Information presented and coverage of each toxin
follows the following distribution: background and toxicology
(10%); chemistry, biochemistry and metabolism (75%); mechanism of
action (10%); and analytical methodology (5%).
The detailed information on chemistry in Phycotoxins: Chemistry and Biochemistry provides investigators, regulators, food technologists and toxicologists an updated basis on which research in other areas such as toxicology, mechanism of action, analytical methodology and pharmacology can be successfully developed and expanded.
2. Brevetoxins: Structure, Toxicology and Origin (Ambrose Furey, Keith O’Callaghan, Javier García Fernández, Mary Lehane, Mónica Fernández Amandi, and Kevin J. James).
3. Chemistry of Maitotoxin (Masayuki Satake).
4. Biochemistry of Maitotoxin (Laura A. de la Rosa, Emilio Alvarez-Parrilla, and Alejandro Martínez).
5. The Chemistry of Palytoxins and Ostreocins (Panagiota Katikou).
6. Biochemistry of Palytoxins and Ostreocins (Carmen Vale and Isabel R. Ares).
7. Chemistry of Cyanobacterial Neurotoxins – Anatoxin-a: Synthetic Approaches (Nuria Armesto Arbella, Keith O’Callaghan, Ambrose Furey, and Kevin J. James).
8. Anatoxin-a and Analogues: Discovery, Distribution and Toxicology (Kevin J. James, Janet Crowley, Mary Lehane, and Ambrose Furey).
9. Pectenotoxins (Christopher Miles).
10. Chemistry, Orgins and Distribution of Yessotoxin and its Analogues (Philipp Hess and John A.B. Aasen).
11. Pharmacology of Yessotoxin (Amparo Alfonso and Carmen Alfonso).
12. Chemistry of Diarrhetic Shellfish Poisoning Toxins (Paulo Vale).
13. The Molecular and Integrative Basis to Domoic Acid Toxicity (John Ramsdell).
14. Hepatotoxic Cyanobacteria (Ana Gago).
15. Polycavernosides (Leo A. Paquette and Mari Yamashita.
16. Structural Assignment and Total Synthesis of Azaspiracid-1 (K.C. Nicolaou, Michael O. Frederick, Kevin P. Cole, Goran Petrovic, and Eriketi Loizidou).
17. Biochemistry of Azaspiracid Poisoning Toxins (Natalia Vilariño).
18. The Cyclic Imines: An Insight into this Emerging Group of Bioactive Marine Toxins (Jordi Molgo and Emmanuelle Girard, and Evelyne Benoit).
- Describes 16 phycotoxins as to chemistry, biochemistry, origin,
toxicology, and analytical methodology
- Coverage extends to mechanistic aspects of newer and emerging
- Updates research knowledge base for investigators, regulators,
food technologists and toxicologists
- Internationally respected editors and contributors