Kinase Inhibitor Drugs
This price is valid for United States. Change location to view local pricing and availability.
Other Available Formats: E-book
Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl kinase inhibitor Gleevec in the treatment of chronic myelogenous leukemia and seven additional marketed kinase inhibitor drugs, researchers have compelling evidence that kinase inhibitors can be highly efficacious in the treatment of diseases caused by aberrant activity of protein kinase. Currently more than 100 protein kinase inhibitors are in clinical development.
In one comprehensive volume, the editors, Dr. Rongshi Li and Dr. Jeffrey Stafford, present timely and important case studies of marketed kinase drugs and several of the most advanced kinase inhibitors in clinical trials. Kinase Inhibitor Drugs includes:
Case studies from leading investigators and experts in the field that provide firsthand accounts of kinase inhibitor discovery
Current thinking on kinase structure, biochemistry, and signal transduction pathways
Information on state-of-the-art technologies and tools such as structure-based and fragment-based drug discovery
A lineup of clinical-phase growth factor receptor inhibitors
Inhibitors of cell cycle kinases
The discovery of allosteric inhibitors of MEK kinase
Information on pharmacogenomics and its application to kinase inhibitor clinical development
Buy Both and Save 25%!
Kinase Inhibitor Drugs (US $145.00)
-and- Carbohydrate Recognition: Biological Problems, Methods, and Applications (US $141.00)
Total List Price: US $286.00
Discounted Price: US $214.50 (Save: US $71.50)