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Bacillus anthracis and Anthrax

ISBN: 978-0-470-41011-0
337 pages
December 2010, Wiley-Blackwell
Bacillus anthracis and Anthrax (0470410116) cover image
The study of Bacillus Anthracis remains at the forefront of microbiology research because of its potential use as a bioterror agent and its role in shaping our understanding of bacterial pathogenesis and innate immunity. Bacillus Anthracis and Anthrax provides a comprehensive guide to all aspects of the organism, ranging from basic biology to public health issues associated with anthrax. This book will be a premier reference for B. Anthracis and anthrax to microbiologists, medical and public health professionals, bioterror research and preparedness, immunologists, and physiologists.
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Preface.

Contributors.

1. Anthrax from 5000 BC to AD 2010 (Peter C. B. Turnbull and Sean V. Shadomy).

2. Outer Structures of the Bacillus anthracis Spore (Adam Driks and Michael Mallozzi).

3. Anthrax Spore Germination (Nathan Fisher, Katherine A. Carr, Jonathan D. Giebel, and Philip C. Hanna).

4. Genetic Manipulation Methods in Bacillus anthracis (Brian K. Janes and Scott Stibitz).

5. The Bacillus anthracis Genome (Timothy D. Read).

6. Bacillus anthracis Plasmids: Species Definition or Niche Adaptation? (David A. Rasko).

7. Iron Acquisition by Bacillus anthracis (Gleb Pishchany and Eric P. Skaar).

8. Anthrax Toxins (Mahtab Moayeri and Stephen H. Leppla).

9. Bacillus anthracis Virulence Gene Regulation (Jason M. Rall and Theresa M. Koehler).

10. The Interactions between Bacillus anthracis and Macrophages (Susan L. Welkos, Joel A. Bozue, and Christopher K. Cote).

11. Bacillus anthracis and Dendritic Cells: A Complicated Battle (Jean-Nicolas Tournier and Anne Quesnel-Hellmann).

12. Bacillus anthracis Dissemination through Hosts (Ian J. Glomski).

13. Pathology, Diagnosis, and Treatment of Anthrax in Humans (Jeannette Guarner and Carlos del Rio).

14. Anthrax Vaccines (Elke Saile and Conrad P. Quinn).

15. Anthrax as a Weapon of War and Terrorism (Leonard A. Cole).

Index.

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"Otherwise, presentation is good, and the running heads that allow navigation within chapters are helpful." (Society for General Microbiology, 25 May 2011)

"Microbiologists, pathologists, and other biological researchers provide a reference on the pathogen and its disease that incorporates the new information and understandings provided by such innovations as gene sequencing, improved animal models, and efficient methods for genetic manipulation; all backed by the massive funding and accelerated research associated with The global war on terror after the still-unsolved anthrax attack on opposition politicians in 2001. Their topics include the outer structure of the Bacillus anthracis spore, the genome, iron acquisition by the bacteria, anthrax toxins, interactions with macrophages, dissemination through hosts, vaccines, and anthrax as a weapon of war and terrorism." (Reference and Research Book News, February 2011)

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January 12, 2011
Bacillus Anthracis and Anthrax

Few strands of bacteria have achieved such a central place in public consciousness as Bacillus anthracis, the bacteria which causes Anthrax. While today it is a feared weapon of bioterrorism Bacillus anthracis has played a significant historical role, especially through the research of the celebrated 19th century scientists Robert Koch and Louis Pasteur, in shaping our understanding of infectious diseases and immunology.

In his new book Bacillus Anthracis and Anthrax Dr Nicholas Bergman brings both of these perspectives together to present a definitive ‘state of the field’ summary for anthrax research, providing a comprehensive guide to all aspects of the organism, ranging from basic biology to central public health issues.

“With all the attention and research that have been focused on Bacillus anthracis and anthrax in recent years, our understanding of both the organism and the disease has improved dramatically,” said Bergman. “This book aims to provide a up-to-date reference that will be useful to scientists, medical and public health personnel, and those playing roles in shaping public policy.” 

Bacillus Anthracis and Anthrax covers all major aspects of Anthrax biology, from basic biology and pathogenesis to diagnosis, treatment, and prevention of anthrax bioterror-associated issues.

Throughout the book anthrax is considered historically as well biologically, with chapters ranging from the impact of anthrax on human history from 5000 BC by Peter Turnbull and Sean Shadomy, to an assessment of current anthrax vaccination research by Elke Saile and Conrad Quinn, as well as an analysis by Leonard Cole of anthrax as a weapon of war.

The biological analysis of B. anthracis, includes research on life cycle, differentiation, cellular structure, as well as the interaction of B. anthracis with the immune system.

Bacillus Anthracis and Anthrax also considers the clinical features, diagnosis and treatment of the different forms of human anthrax, as well as a review of animal models of anthrax and their use in research.

While Bacillus Anthracis and Anthrax will be a premier reference tool to B. Anthracis and anthrax for microbiologists, immunologists and physiologists it will also serve as an invaluable resource for medical professionals, bioterror experts and all those involved in the issues of public health

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