Lyme Borreliosis in Europe and North America: Epidemiology and Clinical Practice

Acknowledgment ix

Contributors xi

1 THE EMERGENCE AND EPIDEMIOLOGY OF LYME BORRELIOSIS IN EUROPE AND NORTH AMERICA 1
Sunil K. Sood, Susan O'Connell, and Klaus Weber

2 THE SPIROCHETES AND VECTOR TICKS OF LYME BORRELIOSIS IN NATURE 37
Joseph Piesman and Pierre-Francois Humair

3 EARLY LYME BORRELIOSIS 53
Vijay K. Sikand and Robert R. Mu¨llegger

4 LYME CARDITIS 81
Fadi A. Haddad and Sunil K. Sood

5 NERVOUS SYSTEM LYME BORRELIOSIS 93
John J. Halperin and Leif Dotevall

6 LYME ARTHRITIS 115
Frank Dressler, Patricia I. Irigoyen, Norman T. Ilowite, and Hans-Iko Huppertz

7 BORRELIAL LYMPHOCYTOMA AND ACRODERMATITIS CHRONICA ATROPHICANS 135
Mark B. Salzman and Robert R. Mullegger

8 LYME BORRELIOSIS COINFECTIONS WITH ANAPLASMA AND BABESIA 149
Paul M. Lantos and Peter J. Krause

9 THE ROLE OF CULTURE AND NUCLEIC ACID AMPLIFICATION IN DIAGNOSIS OF LYME BORRELIOSIS 159
Gary P. Wormser and Guiqing Wang

10 SERODIAGNOSIS OF LYME BORRELIOSIS 185
Barbara J. B. Johnson, Maria E. Aguero-Rosenfeld, and Bettina Wilske

11 PROGNOSIS OF PERSONS WITH LYME BORRELIOSIS 213
Eugene D. Shapiro and Sunil K. Sood

12 PREVENTION OF LYME BORRELIOSIS 225
Sunil K. Sood

Index 245