Asthma: Critical Debates
April 2008, Wiley-Blackwell
As with the other 'Challenges' books, 'Challenges in Asthma' is aimed at hospital specialists and therefore assumes a certain level of knowledge about the disease. It builds on this by discussing only areas of controversy and uncertainty in both the basic understanding of asthma and its management. An international author list will provide stimulating debate with, and ultimately draw some conclusions from, existing data which will benefit readers in their day-to-day practice.
PART 1: Epidemiology.
1. Why is the incidence of asthma increasing (P.M. Matricardi and S. Bonini).
2. Why is asthma more common in the West (E. Von Mutius).
3. How much asthma can be attributed to atopic sensitization (R. Beasley, J. Douwes, J. Pekkanen and N.E. Pearce).
4. Is air pollution important in asthma (A.J. Chauhan).
PART 2: Pathophysiology.
5. Is infection important in the pathogenesis and clinical expression of asthma (E.R. Sutherland and R.J. Martin).
6. Does infection in early life protect against or cause asthma (B. Bjorksten).
7. Does asthma progress to chronic obstructive pulmonary disease (S.T. Weiss).
8. Antenatal factors in the development of atopy and asthma (P.G. Woodruff, S.L. Prescott, P.G. Holt and J.V. Fahy).
9. Genetics of asthma: What’s new (I. Sayers, B. Beghe, J. Holloway and S.T. Holgate).
PART 3: Treatment.
10. Can airway fibrosis be prevented (D. Smallwood and J. Wilson).
11. Does allergen avoidance help? What are the practical measures that patients can take (A. Custovic and A. Woodcock).
12. Is early treatment of children necessary (P.J. Helms).
13. What are the mechanisms of corticosteroid resistance in asthma (P.J. Barnes).
14. What new therapies are being developed for asthma and will they offer something better than steroids (J.C. Kips, K.G. Tournoy and R.A. Pauwels).
15. What is the orel of long-acting ß2 -agonists in the treatment of asthma (M.R. Sears).
16. What is the role of leukotriene modifiers in the treatment of asthma (M.E. Wechsler and J.M. Drazen).
PART 4: Delivery of Care.
17. What are the issues in delivering care in primary care (D. Price).
18. Are asthma clinics useful: should they be run by the doctors or the nurse (B.D.W. Harrison and S.M. Mildenhall).
19. Should asthma be managed by the patient or the doctor: is education important (M.R. Partridge).
20. Are psychosocial factors important in asthma (B.D.W. Harrison and S.M. Mildenhall).
* provides a focus on new and emerging therapies
* includes a topical section devoted to delivery of care
Dr C J Corrigan, Imperial College, London
An absolutely top of the bill list of authors - some young, some
established, but all highly competent.... I have no doubts at all
that such a distinguished list of authors will produce a text of
the highest standard which the enthusiast will be delighted to
Dr Martyn Partridge, Whipps Cross Hospital