Thank you for visiting us. We are currently updating our shopping cart and regret to advise that it will be unavailable until September 1, 2014. We apologise for any inconvenience and look forward to serving you again.

Wiley
Wiley.com
Print this page Share

Drug Resistance in Epilepsy: Lessons from Oncology - No. 243

ISBN: 978-0-470-84146-4
254 pages
April 2002
Drug Resistance in Epilepsy: Lessons from Oncology - No. 243 (047084146X) cover image
The object of this book is to gather together workers in the fields of epilepsy, those concerned with the basic science of resistance and the blood-brain barrier, and those with clinical experience of drug resistance in cancer, with a view to stimulating further work on drug resistance in epilepsy. Whilst resistance in cancer has been extensively studied, and trials of reversal of resistance have been undertaken, with some success, resistance in epilepsy has only just begun to be addressed.
See More
Chair's Introduction (V. Ling).

The problem of the drug-resistant epilepsies (J. W. Sander).

Drug resistance molecules: lessons from oncology (George L. Scheffer and Rik J. Scheper).

Drug resistance in epilepsy: the role of the blood-brain barrier (N. Joan Abbott, et al.).

P glycoprotein and the mechanism of multidrug resistance (A. Varadi, et al).

Drug resistance caused by multidrug resistance-associated proteins (J. Wijnholds).

Reversal of multidrug resistance: lessons from clinical oncology (S. E. Bates, et al.).

Clinical development of P glycoprotein modulators in oncology (A. Oza).

Gene expression profiling of epothilone A-resistant cells (P. Atadja, et al.).

Imaging of P glycoprotein function in vivo with PET (N. H. Hendrikse and W. Vaalburg).

Animal models of drug-resistant epilepsy (W. Loscher).

Drug resistance in epilepsy: human epilepsy (S. M. Sisodiya, et al).

Cellular mechanisms of pharmacoresistance in slices from epilepsy surgery (R. A. Deisz).

Functional polymorphisms of the human multidrug resistance (MDR1) gene: correlation with P glycoprotein expression and activity in vivo (U. Brinkmann).

OC144-093, a novel P glycoprotein inhibitor for the enhancement of anti-epileptic therapy (M. J. Newman, et al.).

Closing remarks (V. Ling).

Index of contributors.

Subject Index.
See More
Buy Both and Save 25%!
+

Drug Resistance in Epilepsy: Lessons from Oncology - No. 243 (US $212.00)

-and- Translational Neuroscience: A Guide to a Successful Program (US $87.95)

Total List Price: US $299.95
Discounted Price: US $224.96 (Save: US $74.99)

Buy Both
Cannot be combined with any other offers. Learn more.
Back to Top