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Metabolism by In Vivo NMR: The Goal of Proteomics
ISBN: 978-0-470-84719-0
Hardcover
206 pages
February 2005
US $180.00 Add to Cart

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  • Description
  • Table of Contents
  • Author Information
Contributors.

Foreword (Sir George K. Radda, Medical Research Council, UK).

Section A: Background.

1 Introduction (Robert G. Shulman).

2 In Vivo NMR Spectroscopy – Techniques; Direct Detection; MRS; Kinetics and Labels; Fluxes; Concentrations (Robin de Graaf).

3 Metabolic Control Analysis for the NMR Spectroscopist (David A. Fell).

Section B: 13C and 31P NMR Studies of the Regulation of Glucose Metabolism.

4 MRS Studies of the Role of the Muscle Glycogen Synthesis Pathway in the Pathophysiology of Type 2 Diabetes (Gerald I. Shulman and Douglas L. Rothman).

5 Phosphorylation of Allosteric Enzymes can serve Homeostasis rather than Control Flux: the Example of Glycogen Synthase (James R.A. Schafer, David A. Fell, Douglas Rothman and Robert G. Shulman).

6 Regulation of Glycogen Metabolism in Muscle during Exercise (Thomas B. Price).

7 13C NMR Studies of Heart Glycogen Metabolism (Maren R. Laughlin, Douglas L. Rothman and Robert G. Shulman).

8 Bioenergetics Implication of Metabolic Fluctuation during Muscle Contraction (Thomas Jue).

9 Lactate, Glycogen and Fatigue (Robert G. Shulman and Douglas L. Rothman).

10 Futile Cycling in Yeast: How to Control Gluttony in the Midst of Plenty (Jan den Hollander and Robert G. Shulman).

11 Trehalose Energetics in Yeast Spores (Robert G. Shulman and Jan den Hollander).

12 Metabolic Networks in the Liver by 2H and 13C NMR (A. Dean Sherry and Craig R. Malloy).

13 Summarized Reflections on Metabolism (Robert G. Shulman and James R. A. Schafer).

Index.