Pharmaceutical Process Chemistry for Synthesis: Rethinking the Routes to Scale-Up
Providing insights about process route selection, choice of reagents, and reaction conditions, Pharmaceutical Process Chemistry for Synthesis guides process chemists in identifying best processes for manufacturing these blockbuster drugs as they lose patent protection. Further, it highlights the strategies and methodology that might be useful for expediting the process research and development of the blockbusters of the future.
Written from a refreshingly objective perspective, this book is essential for process chemists who need to devise practical syntheses for increasingly complex drugs in a constantly decreasing time frame.
2 Actos® (Pioglitazone Hydrochloride).
3 Lexapro® (Escitalopram Oxalate).
4 Efferox XR® (Venlafaxine Hydrochloride).
5 Seroquel® (Quetiapine Hemifumarate).
6 Singulair® (Montelukast Sodium).
7 Prevacid® (Lansoprazole).
8 Advair Diskus® (Salmeterol Xinafoate).
9 Lipitor® (Aatorvastatin Calcium).
—Neal G. Anderson, Anderson's Process Solutions LLC and author of Practical Process Research & Development