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Baculovirus Expression Systems and Biopesticides

Michael L. Shuler (Editor), H. Alan Wood (Editor), Robert R. Granados (Editor), Daniel A. Hammer (Editor)
ISBN: 978-0-471-06580-7
259 pages
November 1994
Baculovirus Expression Systems and Biopesticides (0471065803) cover image
Baculovirus Expression Systems and Biopesticides Edited by Michael L. Shuler, H. Alan Wood, Robert R. Granados, and Daniel A. Hammer Baculovirus Expression Systems and Biopesticides provides an integrated perspective on the use of the continually evolving baculovirus-insect cell system in the production of recombinant proteins and genetically engineered pesticides. Divided into three main sections--Developing Effective Virus-Insect Culture Systems, Bioreactor Design and Scale-Up Issues, and Commercial Application of Insect Cell Culture--the book, written by highly regarded editors in the field, describes:
* The molecular biology and genetics of baculoviruses
* The use of baculoviruses as expression systems
* Principles and methods for small- and large-scale insect cultures
* The use of wild type and genetically engineered baculoviruses as viral pesticides
The breadth of coverage in Baculovirus Expression Systems and Biopesticides will meet the needs of molecular biologists, chemical engineers, biotechnologists,virologists, and entomologists.
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Partial table of contents:

DEVELOPING EFFECTIVE BACULOVIRUS-INSECT CULTURE SYSTEMS.

Insect Cell Culture Methods and Their Use in Virus Research (R. Granados & K. McKenna).

Comparison of Mammalian and Insect Cell Cultures (M. Shuler).

Development and Testing of Genetically Improved Baculovirus Insecticides (H. Wood).

BIOREACTOR DESIGN AND SCALE-UP ISSUES.

Overview of Issues in Bioreactor Design and Scale-Up (R. Taticek, et al.).

The Effect of Hydrodynamic Forces on Insect Cells (J. Chalmers).

COMMERCIAL APPLICATION OF INSECT CELL CULTURE.

Baculovirus-Mediated Production of Proteins in Insect Cells: Examples of Scale-Up and Product Recovery (M. Silberklang, et al.).

Index.
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