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Understanding Craniofacial Anomalies: The Etiopathogenesis of Craniosynostoses and Facial Clefting

Mark P. Mooney (Editor), Michael I. Siegel (Editor)
ISBN: 978-0-471-38724-4
583 pages
May 2002
Understanding Craniofacial Anomalies: The Etiopathogenesis of Craniosynostoses and Facial Clefting (047138724X) cover image
This comprehensive textbook, edited by world-renowned experts in the field, provides answers to challenges in the diagnosis and treatment of craniofacial anomalies.The book integrates basic science and clinical perspectives, creating a more unified and practical “patient centered” approach. Organized in a logical, easy-to-follow structure, this reference reviews and presents cutting-edge findings, covering the state of the art in craniosynostosis and facial clefting from molecular, genetic, cellular, tissue, organismic, and populations levels. Using standardized nomenclature and consistent terminology, Understanding Craniofacial Anomalies incorporates the recent explosion of growth in studying genetic and epigenetic etiologies of syndromes, thereby providing a unique and holistic review of this important topic.
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Forward.

Preface.

Contributors.

SECTION I: CLASSIFICATION AND TERMINOLOGY.

Overview and Introduction (M. Mooney & M. Siegel).

Terminology and Classification of Craniosynostosis (M. Jones).

Terminology and Classification of Facial Clefting (R. Shprintzen).

SECTION II: EMBRYOGENESIS AND ETIOLOGY.

Craniofacial Embryogenesis: Normal Developmental Mechanisms (G. Sperber).

Johnston and Bronsky.

Genetic Etiologies of Craniosynostosis (E. Jabs).

Genetic Etiologies of Facial Clefting (M. Marazita).

Environmental Etiologies of Orofacial Clefting and Craniosynostosis (V. Shashi & T. Hart).

SECTION III: ANIMAL MODELING.

Animal Models and Craniosynostosis: Experimental, Congenital, and Transgenic Models (M. Mooney, et al.).

Aniaml Models of Facial Clefting -
Experimental, Congenital, and Transgenic (V. Diewert & S. Lozanoff).

SECTION IV: CRANIAL VAULT AND CRANIAL BASE DYSMORPHOLOGY AND GROWTH DISTURBANCES.

Evolutionary Changes in the Cranial Vault and Base: Establishing the Primate Form (M. Mooney, et al.).

Cranial Base Dysmorphology and Growth in the Craniosynostoses (A. Burdi).

Cranial Base Dysmorphology and Growth in Facial Clefting (T. Smith, et al.).

Cranial Vault Morphology and Growth in Craniosynostosis (J. Richtsmeier).

SECTION V: MIDFACIAL AND MANDIBULAR DYSMORPHOLOGY AND GROWTH DISTURBANCES.

Evolutionary Changes in the Midface and Mandible: Establishing the Primate Form (J. Siebert & D. Swindler).

Facial Dysmorphology in the Craniosynostoses: Clinical Implications (K. Vig).

Midfacial and Mandibular Dysmorphology and Growth in Facial Clefting: Clinical Implications (B. Ross).

SECTION VI: REGIONAL DYSMORPHOLOGY AND GROWTH DISTURBANCES.

Dental Development and Anomalies in Craniosynostoses and Facial Clefting (E. Harris).

Vocal Tract Anatomy and Functional Concequences in Cleft Lip/Palate and Syndromes of Craniosynostosis (S. Peterson-Falzone & P. Monoson).

SECTION VII: MOLECULAR BIOLOGY STUDIES AND FUTURE DIRECTIONS.

Molecular Studies of Craniosynostosis: Factors Affecting Cranial Suture Morphogenesis and Patency (L. Opperman & R. Ogle).

Molecular Studies of Facial Clefting: From Mouse to Man (M. Melnick & T. Jaskoll).

Molecules and Faces: What is on the Horizon? (H. Slavkin).

Index.
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“A very useful book…well written, amply illustrated…” (Journal of Endocrine Genetics, Vol 3 No 3, 2003)

"This book provides an excellent introduction to craniofacial anomalies. It provides a good mix of basic science and clinical aspects and reflects the recent explosion of growth in the knowledge about the study of genetics." (Doody's)

"...A very useful book..." (Journal of Pediatric Endocrinology & Metabolism)

"...appropriately thorough and learned summary of the state of knowledge of craniofacial evolution and embryology...." (Pediatric and Developmental Pathology, Vol. 6, 2002)

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Understanding Craniofacial Anomalies: The Etiopathogenesis of Craniosynostoses and Facial Clefting (US $232.50)

-and- A Companion to the Anthropology of the Body and Embodiment (US $214.95)

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