Individual Online Subscriptions are now available! Visit the How to Order page for more information.

What's New and Updated in Current Protocols in Immunology
Supplement 81, May 2008

UNIT 4.6 Assessment of Lymphocyte Development in Radiation Bone Marrow Chimeras (Updated)
UNIT 15.21 Creation of “Humanized” Mice to Study Human Immunity (New)
UNIT 15.22 The K/BxN Arthritis Model (New)
UNIT 18.15 Characterizing Protein-Protein Interactions by Sedimentation Velocity Analytical Ultracentifrugation (New)
APPENDIX 1X Paired Receptor Systems of the Innate Immune System (New)

Current Protocols in Immunology is a "best-practices" collection that provides comprehensive coverage of immunological methods from classic to the most cutting edge: the most sophisticated protocols in immunology today.

Updated every three months in all formats, CPI is constantly evolving to keep pace with the very latest discoveries and developments. A year of these updates is included in the initial CPI purchase price. That's 770 pages of new (43%) and revised (57%) content on average every year since the initial publication of the work in January 1991! Presently five volumes in its looseleaf print version, CPI...

• covers the latest in antibody detection and preparation, molecular immunology, innate immunity, tumor immunology, engineering immune molecules and receptors, and more.
• includes a recently-added chapter on sources and proven methods for isolation and characterization of stem and progenitor cells, as well as animal models for analyses.
• offers valuable reference information in five extensive appendices, including commonly used reagents, equipment and techniques; and a full appendix devoted to the CD system of leukocyte surface molecules.

Edited by: John E. Coligan (Rockville, MD); Barbara Bierer (Brigham and Women's Hospital and Harvard Medical School); David H. Margulies (Bethesda, MD); Ethan M. Shevach (Bethesda, MD); Warren Strober (Bethesda, MD); Richard Coico (Weill Medical College of Cornell University); Guest Editors: Patricia Brown (Frederick, Maryland); John C. Donovan (Wyeth Research); Past Editor: Ada Kruisbeek (Netherlands Research Institute)

Series Editor: Richard Coico (Temple University)

While the authors, editors, and publisher believe that the specification and usage of reagents, equipment, and devices, as set forth in this book, are in accord with current recommendations and practice at the time of publication, they accept no legal responsibility for any errors or omissions, and make no warranty, express or implied, with respect to material contained herein. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of experimental reagents, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each chemical, piece of equipment, reagent, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. This is particularly important in regard to new or infrequently employed chemicals or experimental reagents. Moreover, the information presented herein is not a substitute for professional judgment, especially as concerns any applications in a clinical setting or the interpretation of results thereby obtained.