This publication is unique and ground breaking because no previous volume has focused on the mechanisms by which nitric oxide and oxygen radicals are involved in vascular pathophysiology. This book provides a current review of the use of nitric oxide to treat pulmonary hypertension, whether idiopathic or secondary to congenital heart disease. In this respect, it should be read by pediatric cardiologists. Respiratory care physicians and intensive-care specialists who study and treat ARDS or IRDS (adult or infant respiratory distress syndromes) would also benefit from this publication. This book is of particular interest to physiologists concerned with vascular biology or with the activity of nitric oxide and oxygen radicals.