1. Historical Overview.

2. Normal Immune Responses.

3. Immune Response to Allografts.

4. Inflamatory Response to Allografts.

5. Mechanisms of Tolerance.

6. Basic Immunogenetics.

7. Clinical Immunogenetics.

8. Xenotransplantation.

II. Pharmacology and Immunosuppression.

9. Historical Overview of Pharmacology and Immunosuppression.

10. Basic Principles of Pharmacology.

11. Principles and Overview of Immunosuppression.

12. Commonly Used Drugs and Drug Interactions.

13. Design and Interpretation of Clinical Trials in Transplantation.

14a. Action, Efficacy and Toxicities: Cyclosporine.

14b. Action, Efficacy and Toxicities: Tacrolimus.

14c. Action, Efficacy and Toxicities: Mycophenolate Mofetil.

14d. Action, Efficacy and Toxicities: Azathioprine.

14e. Action, Efficacy and Toxicities: Corticosteroids.

14f. Action, Efficacy and Toxicities: Polyclonal Antilymphocyte Antibodies.

14g. Action, Efficacy and Toxicities: Anti-CD3 Monoclonal Antibodies.

14h. Action, Efficacy and Toxicities: Anti-CD25 Monoclonal Antibodies.

14i. Action, Efficacy and Toxicities: Rapamycin.

15. Nonbiologics.

16. Investigational Immunosuppressive Agents: Biologicals.

III. Organ Procurement/Economics.

17. Cadaver Donor Management.

18. Economics of Transplantation.

IV. Medical Complications of Transplantation.

19. Heart Disease in Non-Heart Transplant Patients.

20. Principles of Infectious Disease Management for the Organ Transplant Recipient.

21. Kidney Disease in Nonrenal Transplantation.

22. Liver Disease in Non-Liver Transplant Patients.

23. Lung Disease in Non-Lung Transplant Patients.

24. Metabolic Complications.

25. Bone Disease Following Transplantation.

26. Neoplasia Following Transplantation.

27. Transplantation and Reproductive Health.

28. Diseases of the the Skin Following Transplantation.

29. Ocular Complications in Transplant Patients.

30. Long-term Management of the Transplanted Patient: Health Maintenance Issues.

31. Special Issues in Pediatric Organ Transplantation.

V. Heart Transplantation.

32. Historical Overview of Heart Transplantation.

33. Evaluation and Management of Prospective Heart Recipients.

34. Living Heart Donors -- Domino Heart Transplantation.

35. Cadaver Heart Donor Selection Criteria.

36. The Continuing Evolutions of Donor Heart Allocation.

37. Heart Transplantation: Technical Tips to the Surgical Procedure.

38.Immediate Postoperative Management of the Heart Transplant Recipient.

39. Physiology of the Transplanted Heart.

40. Induction Immunosuppression Protocols for Heart Transplantation.

41. Left Ventricular Dysfunction after Cardiac Transplantation: Etiologies, Diagnosis and Treatment.

42. Pathologic Findings of Cardiac Dysfunction.

43. Long-Term Management Issues in Heart Transplantation.

44. Maintenance Immunosuppression Protocols for Heart Transplantation.

45. Expected Clinical Outcomes -- Risk Factors for Heart Transplantation.

46. Special Considerations in Pediatric Heart Transplantation.

47. Heart-Lung Transplantation.

VI. Kidney and Pancreas Transplantation.

48. History of Kidney and Pacreas Transplantation.

49. Evaluation and Management of Prospective Kidney Patients.

50. Living Kidney Donor Evaluation and Selection.

51. Cadaver Kidney Donor Selection.

52. Sharing and Allocation.

53. Technical Aspects of Renal Transplantation.

54. Immediate Postoperative Management of the Kidney Transplant Recipient.

55. Physiology of the Transplanted Kidney.

56. Induction Immunosuppression Protocols for Kidney Transplantation.

57. Diagnosis and Treatment of Renal Dysfunction Episodes.

58. Pathologic Findings of Renal Allogaft Dysfunction.

59. Long-Term Management Issues in Kidney Transplantation.

60. Maintenance Immunosuppression Protocols for Kidney Transplantation.

61. Expected Clinical Outcomes -- Risk Factors in Kidney Transplantation.

62. Special Considerations in Pediatric Kidney Transplantation.

63. Pancrease and Simultaneous Kidney-Pancreas Transplantation.

64. Pancreatic Islet Cell Transplantation.

VII. Liver and Intestinal Transplantation.

65. Historical Overview of Liver Transplantation.

66. Evaluation and Management of Prospective Liver Transplant Candidates.

67. Living-Related Liver Transplantation: Selection and Recipient Donors.

68. Cadaver Liver Donor Selection Criteria.

69. Liver Donor Allocation Scheme.

70. Surgical Techniques in Liver Transplantation.

71. Immediate Postoperative Management of the Liver Transplant Patient.

72. Physiology of the Transplanted Liver.

73. Induction Immunosuppression Protocols for Liver Transplantation.

74. Diagnosis and Treatment of Hepatic Allograft Dysfunction.

75. The Histopathology of Liver Allograft Dysfunction.

76. Long-Term Issues in Liver Transplantation.

77. Mantenance Immunosuppression for Liver Transplantation.

78. Expected Clinical Outcomes/Risk Factores for Liver Transplantation.

79. Special Considerations in Pediatric LIver Transplantation.

80. Clinical Intestinal Transplantation: Recent Advances and Future Consideration.

81. Hepatocyte Transplantation.

VIII. Lung Transplantation.

82. Lung Transplantation - Historical Perspective.

83. Evaluation and Mangement of Prospective Lung and Lung-Heart Recipients.

84. Living-Donor Lobar Lung Transplantation: Donor Evaluation and Selection.

85. Living-Donor Lung Transplantation: Surgical Technique and Perioperative Management.

86. Cadaver Lung Donor Selection Criteria.

87. Cadaver Lung Donor Allocation Scheme.

88. Lung and Heart-Lung Transplant Surgical Procedure.

89. Immediate Postoperative Management of the Lung Transplant Recipient.

90. Physiology of the Transplanted Lung.

91. Induction Immunosuppression Protocols for Lung Transplantation.

92. Diagnosis and Treatment of Pulmonary Dysfunction Episodes.

93. Pathology of Pulmonary Allograft Dysfunction.

94. Long-Term Management Issues in Lung Transplantation.

95. Maintenance Immunosuppression Protocols for Lung Transplantation.

96. Lung Transplantation: Outcomes.

97. Pediatric Lung Transplantation: Special Considerations and Remaining Hurdles