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Handbook of Biomedical Telemetry

ISBN: 978-1-118-38861-7
736 pages
August 2014, Wiley-IEEE Press
Handbook of Biomedical Telemetry (1118388615) cover image

Description

A must-have compendium on biomedical telemetry for all biomedical professional engineers, researchers, and graduate students in the field

Handbook of Biomedical Telemetry describes the main components of a typical biomedical telemetry system, as well as its technical challenges. Written by a diverse group of experts in the field, it is filled with overviews, highly-detailed scientific analyses, and example applications of biomedical telemetry. The book also addresses technologies for biomedical sensing and design of biomedical telemetry devices with special emphasis on powering/integration issues and materials for biomedical telemetry applications.

Handbook of Biomedical Telemetry:

  • Describes the main components of a typical biomedical telemetry system, along with the technical challenges
  • Discusses issues of spectrum regulations, standards, and interoperability—while major technical challenges related to advanced materials, miniaturization, and biocompatibility issues are also included
  • Covers body area electromagnetics, inductive coupling, antennas for biomedical telemetry, intra-body communications, non-RF communication links for biomedical telemetry (optical biotelemetry), as well as safety issues, human phantoms, and exposure assessment to high-frequency biotelemetry fields
  • Presents biosensor network topologies and standards; context-aware sensing and multi-sensor fusion; security and privacy issues in biomedical telemetry; and the connection between biomedical telemetry and telemedicine
  • Introduces clinical applications of Body Sensor Networks (BSNs) in addition to selected examples of wearable, implantable, ingestible devices, stimulator and integrated mobile healthcare system paradigms for monitoring and therapeutic intervention

Covering biomedical telemetry devices, biosensor network topologies and standards, clinical applications, wearable and implantable devices, and the effects on the mobile healthcare system, this compendium is a must-have for professional engineers, researchers, and graduate students.

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Table of Contents

PREFACE xxi

ACKNOWLEDGMENTS xxiii

CONTRIBUTORS xxv

1 Introduction to Biomedical Telemetry 1
Konstantina S. Nikita

1.1 What is Biomedical Telemetry? 1

1.2 Significance of Area, 3

1.3 Typical Biomedical Telemetry System, 4

1.4 Challenges in Biomedical Telemetry, 5

1.5 Commercial Medical Telemetry Devices, 14

1.6 Overview of Book, 19

References, 23

PART I BIOMEDICAL TELEMETRY DEVICES 27

2 Design Considerations of Biomedical Telemetry Devices 29
Dominik Cirmirakis and Andreas Demosthenous

2.1 Introduction, 29

2.2 Energy Transfer Types, 30

2.3 Architecture of Inductively Coupled Biomedical Telemetry Devices, 31

2.4 Data Transmission Methods, 39

2.5 Safety Issues, 44

2.6 Conclusion, 51

References, 51

3 Sensing Principles for Biomedical Telemetry 56
Athanasios Lioumpas, Georgia Ntouni, and Konstantina S. Nikita

3.1 Introduction, 56

3.2 Biosensor Structure, 57

3.3 Electrochemical Biosensors, 59

3.4 Optical Biosensors, 63

3.5 Thermal/Calorimetric Biosensors, 67

3.6 Piezoelectric Biosensors, 69

3.7 Other Types of Biosensors, 71

3.8 Conclusions, 72

References, 73

4 Sensing Technologies for Biomedical Telemetry 76
Toshiyo Tamura

4.1 Introduction, 76

4.2 Noninvasive Sensors and Interfaces, 77

4.3 Invasive and Implantable Sensors, 92

4.4 Conclusion, 101

References, 101

5 Power Issues in Biomedical Telemetry 108
Manos M. Tentzeris, Rushi Vyas,WeiWei, Yoshihiro Kawahara, Li Yang, Stavros Georgakopoulos, Vasileios Lakafosis, Sangkil Kim, Hoseon Lee, Taoran Le, Sagar Mukala, and Anya Traille

5.1 Introduction and Powering Mechanisms, 108

5.2 Motion-Powered Radio Frequency Identification (RFID) Wireless Sensors, 109

5.3 Noninvasive Wireless Methods for Powering on Sensors, 112

5.4 Conclusion, 129

References, 129

PART II PROPAGATION AND COMMUNICATION ISSUES FOR BIOMEDICAL TELEMETRY 131

6 Numerical and Experimental Techniques for Body Area Electromagnetics 133
Asimina Kiourti and Konstantina S. Nikita

6.1 Introduction, 133

6.2 Electrical Properties of Human Body Tissues, 135

6.3 Numerical Modeling, 139

6.4 Physical Modeling, 154

6.5 Safety Issues, 164

6.6 Conclusion, 167

References, 168

7 Inductive Coupling 174
Maysam Ghovanloo and Mehdi Kiani

7.1 Introduction, 174

7.2 Induction Principles, 175

7.3 Wireless Power Transmission, 178

7.4 Inductive Coupling for Biomedical Telemetry, 186

7.5 Inductive Data Transmission, 192

7.6 Broader Applications, 201

7.7 Future Research Directions, 202

7.8 Conclusion, 202

References, 203

8 Antennas and RF Communication 209
Asimina Kiourti and Konstantina S. Nikita

8.1 Introduction, 209

8.2 Background Information, 211

8.3 On-Body Antennas, 212

8.4 Implantable Antennas, 223

8.5 Ingestible Antennas, 235

8.6 Conclusion and Future Research Directions, 245

References, 246

9 Intrabody Communication 252
Laura M. Roa, Javier Reina-Tosina, Amparo Callejón-Leblic, David Naranjo, and Miguel Á. Estudillo-Valderrama

9.1 Introduction, 252

9.2 Intrabody Communication Transmission Methods, 256

9.3 Dielectric Properties of Human Body, 259

9.4 Experimental Characterization of IBC Channel, 265

9.5 Introduction to IBC Models, 273

9.6 IBC Propagation Channel, 282

9.7 Conclusion, 292

Acknowledgments, 294

References, 294

10 Optical Biotelemetry 301
Koichi Shimizu

10.1 Introduction, 301

10.2 Optical Technology for Optical Biotelemetry, 303

10.3 Communication Technology for Optical Telemetry, 306

10.4 Propagation of Optical Signal, 309

10.5 Multiplexing in Optical Telemetry, 313

10.6 Applications of Optical Telemetry, 316

10.7 Conclusion, 327

References, 328

11 Biosensor Communication Technology and Standards 330
Lars Schmitt, Javier Espina, Thomas Falck, and Dong Wang

11.1 Introduction, 330

11.2 Biosensor Application Scenarios, 332

11.3 Biosensor Communication Technologies, 335

11.4 Conclusion, 364

References, 365

12 Context-Aware Sensing and Multisensor Fusion 368
Stefan Hey

12.1 Introduction, 368

12.2 Context-Aware Sensing, 368

12.3 Multisensor Fusion, 373

12.4 Example Application: Stress Measurement, 378

12.5 Conclusion and Future Research Directions, 379

References, 379

13 Security and Privacy in Biomedical Telemetry: Mobile Health Platform for Secure Information Exchange 382
Nikolaos Bourbakis, Alexandros Pantelopoulos, and Raghudeep Kannavara

13.1 Introduction, 382

13.2 Digital Security, 383

13.3 Wearable Health Monitoring Systems (WHMS) Platform, 390

13.4 Processing of Physiological Data, 394

13.5 Secure Information Exchange, 400

13.6 Conclusion and Future Research Directions, 414

Acknowledgment, 415

References, 415

14 Connection Between Biomedical Telemetry and Telemedicine 419
Emmanouil G. Spanakis, Vangelis Sakkalis, Kostas Marias, and Manolis Tsiknakis

14.1 Introduction, 419

14.2 Biomedical Instrumentation, 420

14.3 Biomedical Telemetry and Telemedicine: Related Work, 421

14.4 Theory and Applications of Biomedical Telemetry, 423

14.5 Integration of Biomedical Telemetry with Telemedicine, 423

14.6 Wireless Communication Protocols and Standards, 425

14.7 Cross-Layer Design of Wireless Biomedical Telemetry and Telemedicine Health Networks, 425

14.8 Telecommunication Networks in Health Care for Biomedical Telemetry, 428

14.9 Future Research Directions and Challenges, 437

14.10 Conclusion, 440

References, 442

15 Safety Issues in Biomedical Telemetry 445
Konstantinos A. Psathas, Asimina Kiourti, and Konstantina S. Nikita

15.1 Introduction, 445

15.2 Operational Safety, 446

15.3 Product and Device Hazards, 450

15.4 Patient and Clinical Safety, 454

15.5 Human Factor and Use Issues, 458

15.6 Electromagnetic Compatibility and Interference Issues, 461

15.7 Applicable Guidelines, 464

15.8 Occupational Safety, 471

15.9 Future Research Directions, 472

15.10 Conclusion, 473

References, 474

PART III EXAMPLE APPLICATIONS OF BIOMEDICAL TELEMETRY 479

16 Clinical Applications of Body Sensor Networks 481
Richard M. Kwasnicki and Guang-Zhong Yang

16.1 Introduction, 481

16.2 Healthcare Paradigm Shift for Pervasive Sensing, 483

16.3 Usage Scenarios, 484

16.4 Opportunities and Future Challenges, 494

16.5 Conclusion, 501

Acknowledgment, 502

References, 502

17 Wearable Health Care System Paradigm 505
Yang Hao and Robert Foster

17.1 Introduction, 505

17.2 Wireless Wearable Technology in Health Care, 506

17.3 Methods and Design Approach for Wireless Wearable Systems, 509

17.4 Example Wireless Body Area Network (WBAN) Applications in Health Care, 516

17.5 Conclusion, 521

References, 521

18 Epidermal Sensor Paradigm: Inner Layer Tissue Monitoring 525
Dimitris Psychoudakis, Chi-Chih Chen, Gil-Young Lee, and John L. Volakis

18.1 Introduction, 525

18.2 Review of Electromagnetic Properties of Human Body, 526

18.3 Propagation Modes for Body-Centric Wireless Communications, 531

18.4 Human Torso Model for Body-Centric Wireless Communication, 537

18.5 Two-Layer Model for Internal Organ Monitoring, 542

18.6 Epidermal RF Sensor for Inner Layer Tissue Monitoring, 542

18.7 Extraction of Dielectric Constant, 544

18.8 Conclusion, 546

References, 547

19 Implantable Health Care System Paradigm 549
Masaharu Takahashi and Koichi Ito

19.1 Introduction, 549

19.2 Multilayered Model Simulating Human Body, 550

19.3 Cardiac Pacemaker Embedded in Multilayered Models, 554

19.4 Implantable Health Care System Paradigm, 562

19.5 Conclusion and Future Research Directions, 568

References, 570

20 Ingestible Health Care System Paradigm forWireless Capsule Endoscopy 572
Nikolaos Bourbakis and Alexandros Karargyris

20.1 Introduction, 572

20.2 WCE and Endoscopic Imaging, 576

20.3 Diagnostic Methods and Challenges, 585

20.4 Future Directions: Design New Generation of WCE, 586

20.5 Conclusion and WCE Global Health Care, 591

References, 591

21 Stimulator Paradigm: Artificial Retina 593
Carlos J. Cela, Keyoor C. Gosalia, Anil Kumar RamRakhyani, Gianluca Lazzi, Shruthi Soora, Gerard J. Hayes, and Michael D. Dickey

21.1 Introduction, 593

21.2 Telemetry for Artificial Retina, 594

21.3 Intraocular Telemetry Antennas, 595

21.4 Multicoil Telemetry, 611

21.5 Future Research Directions: Flexible and Liquid Antennas, 618

21.6 Conclusion, 620

References, 620

22 mHealth-Integrated System Paradigm: Diabetes Management 623
Alessio Fioravanti, Giuseppe Fico, Alejandro González Patón, Jan-Paul Leuteritz, Alejandra Guillén Arredondo, and María Teresa Arredondo Waldmeyer


22.1 Clinical Treatment, 623

22.2 Diabetes Treatment through Telemetry, 624

22.3 Problems Related to Current Treatments, 625

22.4 Assessment: State of the Art, 625

22.5 Technological Solution, 626

22.6 METABO System, 627

22.7 Evaluation Methodology: Data Collection and System Testing, 629

22.8 Results, 631

22.9 Conclusion, 631

Acknowledgments, 632

References, 632

23 Advanced Material-Based Sensing Structures 633
Manos M. Tentzeris, Sangkil Kim, Vasileios Lakafosis, Hoseon Lee, Taoran Le, Rushi Vyas, Sagar Mukala, and Anya Traille

23.1 Introduction, 633

23.2 Human-Body-Wearable Antennas, 634

23.3 Carbon-Nanotube-Based Ammonia Detection for Medical Diagnosis, 656

23.4 Graphene-Based Ammonia Detection for Medical Diagnosis, 670

23.5 Integrated Wireless Modules, 679

23.6 Conclusion, 685

References, 686

INDEX 691

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Author Information

KONSTANTINA S. NIKITA is a Professor within the School of Electrical and Computer Engineering at NTUA (National Technical University of Athens). She has authored or coauthored six books, 170 papers in refereed international journals, and over 300 papers in international conference proceedings. The holder of two patents, Dr. Nikita is a senior member of the Institute of Electrical and Electronics Engineers (IEEE); an Associate Editor of the IEEE Transactions on Biomedical Engineering, the Journal of Biomedical and Health Informatics, and the Bioelectromagnetics Journal; a member of the EMBS BHI Technical Committee; the Founding Chair and Ambassador of the IEEE-Engineering in Medicine and Biology Society, Greece Chapter; and Vice Chair of the IEEE Greece Section.

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