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Pancreatitis: Medical and Surgical Management

David B. Adams (Editor), Peter B. Cotton (Editor), Nicholas J. Zyromski (Editor), John A. Windsor (Editor)
ISBN: 978-1-118-91712-1
336 pages
April 2017, Wiley-Blackwell
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Description

Pancreatitis: medical and surgical management provides gastroenterologists and GI surgeons, both fully qualified and in training, with a focused, evidence-based approach to the most exciting developments in the diagnosis and clinical management of pancreatitis.

Focusing mainly on the rapidly changing and innovative medical and surgical strategies to manage the disease, new surgical procedures such as endoscopic biliary intervention and minimally invasive necrosectomy to exciting new medical therapies like Antiprotease, Lexipafant, probiotics and enzyme treatment are all discussed.

Full colour throughout, with over 250 colour illustrations and with reference to the latest clinical guidelines from the AGA, ACG and UEGW at all times, it is an essential consultation tool for all those managing patients with this increasingly common condition.

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Table of Contents

List of contributors, vii

1 Epidemiology and genetics of chronic pancreatitis, 1

2A Pathobiology of the acinar cell in acute pancreatitis, 10

2B Locoregional pathophysiology in acute pancreatitis: pancreas and intestine, 19

2C Pathophysiology of systemic inflammatory response syndrome and multiorgan dysfunction syndrome in acute pancreatitis, 29

3 Diagnosis, prediction, and classification, 38

4 Medical treatment, 47

5 Nutritional treatment in acute pancreatitis, 55

6 Gallstone pancreatitis: diagnosis and treatment, 64

7 Treatment of local complications, 75

8 Treatment of systemic complications and organ failure, 85

9 Specific treatment for acute pancreatitis, 91

10 Sequelae of acute pancreatitis, 101

11 History of chronic pancreatitis, 113

12A Epidemiology and pathophysiology: epidemiology and risk factors, 118

12B Epidemiology and pathophysiology: genetic insights into pathogenesis, 126

12C Pancreatic stellate cells: what do they tell us about chronic pancreatitis?, 143

12D Autoimmune pancreatitis: an update, 152

12E Etiology and pathophysiology: tropical pancreatitis, 161

12F Mechanisms and pathways of pain in chronic pancreatitis, 169

13A Imaging of chronic pancreatitis, 179

13B Endoscopic ultrasonography in chronic pancreatitis, 188

14A Pancreatic enzyme replacement therapy (PERT), 195

14B Nutritional treatment: antioxidant treatment, 205

14C Pancreatogenic diabetes: etiology, implications, and management, 211

14D Nutrition without a pancreas: how does the gut do it?, 225

15A Endoscopic management of chronic pancreatitis, 233

15B Shocking and fragmenting pancreatic ductal stones, 245

15C Endoscopic management: celiac plexus blockade, 249

16A A brief history of modern surgery for chronic pancreatitis, 256

16B Surgery for chronic pancreatitis: indications and timing of surgery, 261

16C Chronic pancreatitis: surgical strategy in complicated diseases, 265

16D Surgery for chronic pancreatitis: pancreatic duct drainage procedures, 273

16E Surgical management: resection and drainage procedures, 279

16F The role of pancreatoduodenectomy in the management of chronic pancreatitis, 286

17A Total pancreatectomy and islet cell autotransplantation: patient selection, 295

17B Total pancreatectomy and islet cell autotransplantation: the science of islet cell preservation, from pancreas to liver, 299

17C Total pancreatectomy and islet cell autotransplantation: long-term assessment of graft function, 308

Index, 321

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Reviews

"Overall, this is an excellent book on all aspects of acute and chronic pancreatitis. It is concise yet comprehensive, written by well-known and well-published, credible authorities. It will be useful not just to the intended audience of gastroenterologists and GI surgeons, but also to all physicians involved in the care of patients with pancreatitis. Most books try to cover all aspects of this complex condition in a summary fashion, which is not possible. This book fills in the gaps by providing a focused, comprehensive review including latest evidence and guidelines. 5 Stars!" (Doody Enterprises July 2017)

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