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Polymers for Biomedicine: Synthesis, Characterization, and Applications

Carmen Scholz (Editor)
ISBN: 978-1-118-96657-0
624 pages
July 2017
Polymers for Biomedicine: Synthesis, Characterization, and Applications (1118966570) cover image


Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules.

•    Aids researchers developing polymers and materials for biomedical applications
•    Describes biopolymers from a synthetic perspective, which other similar books do not do
•    Covers areas that include: cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification
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Table of Contents

List of Contributors

Part I. Pseudo-Peptides, Polyamino acids and Polyoxazolines

Chapter 1 - Characterization of Polypeptides and Polypeptoides­ –Methods and Challenges
David Huesmann and Matthias Barz

Chapter 2- Poly(2-Oxazoline): The structurally Diverse Biocompatibilizing Polymer
Rodolphe Obeid

Chapter 3- Poly(2-oxazoline) Polymers – synthesis, characterization and Applications in Development of Therapeutics
Randall W. Moreadith and Tacey X. Viegas

Chapter 4- Polypeptoid Polymers: Synthesis, Characterization and Properties
Brandon A. Chan, Sunting Xuan, Ang Li, Jessica M. Simpson and Donghui Zhang

Part II - Advanced Polycondensates

Chapter 5 - Polyanhydrides: Synthesis and Characterization
Rohan Ghadi, Eameema Muntimadugu Wahid Khan and Abraham J. Domb

Chapter 6 - New Routes to Tailor-Made Polyesters
Kazuki Fukushima and Tomoko Fujiwara

Chapter 7 - Polyphosphoesters: An old biopolymer in a new light
Kristin N. Bauer, Hisaschi T.C. Tee, Evandro M. Alexandrino and Frederik R. Wurm

Part III. Cationically Charged Macromolecules

Chapter 8 - Design and Synthesis of Amphiphilic Vinyl Copolymers with Antimicrobial Activity
Leanna L. Foster, Masato Mizutani, Yukari Oda, Edmund F. Palermo and Kenichi Kuroda

Chapter 9 - Enhanced Polyethylenimine-Based Delivery of Nucleic Acids
Jeff Sparks, Tooba Anwer and Khursheed Anwer

Chapter 10 - Cationic graft copolymers for DNA engineering
Atsushi Maruyama and Naohiko Shimada

Part IV. Biorelated polymers by Controlled Radical Polymerization

Chapter 11 - Synthesis of (Bio)degradable Polymers by Controlled/“Living” Radical Polymerization"
Shannon R. Woodruff and Nicolay V. Tsarevsky

Part V. Polydrugs and Polyprodrugs

Chapter 12 - Polymerized drugs – a novel approach to controlled release systems
B. Demirdirek, J. J. Faig, R. Guliyev and K.E.Uhrich

Chapter 13 - Structural design and synthesis of polymer prodrugs
Petr Chytil, Libor Kostka and Tomáš Etrych

Part VI. Biocompatibilization of Surfaces

Chapter 14 - Polymeric ultrathin films for surface modifications
Henning Menzel

Chapter 15 - Surface Functionalization of Biomaterials by Poly(2-oxazoline)s
Giulia Morgese and Edmondo M. Benetti

Chapter 16 - Biorelated polymer brushes by surface initiated reversible deactivation radical polymerization
Rueben Pfukwa, Lebohang Hlalele and Bert Klumperman

Part VII. Self-assembled Structures and Formulations

Chapter 17 - Synthesis of amphiphilic invertible polymers for biomedical applications
A.M. Kohut, I.O. Hevus, S.A. Voronov and A.S. Voronov

Chapter 18 - Bioadhesive Polymers for Drug Delivery
Eenko Larrañeta and Ryan F. Donnelly


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Author Information

CARMEN SCHOLZ, PhD, is a Professor in the Department of Chemistry at the University of Alabama in Huntsville, where her research concentrates on the synthesis and characterization of biocompatible and biodegradable polymers. She serves on the editorial boards of 3 journals (including Wiley's Polymer International), has published over 70 papers or proceedings, and edited 5 books.

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