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Dermatopathology: Diagnosis by First Impression, 3rd Edition

ISBN: 978-1-119-14945-3
344 pages
October 2016, Wiley-Blackwell
Dermatopathology: Diagnosis by First Impression, 3rd Edition (1119149452) cover image


The atlas that helps you differentiate visually similar diseases

Written with the dermatology trainee in mind, Dermatopathology: Diagnosis by First Impression uses more than 800 high resolution color images to introduce a simple and effective way to defuse the confusion caused by dermatopathology slides. Focused on commonly tested entities, and using low- to high-power views, this atlas emphasizes the key differences between visually similar diseases by using appearance as the starting point for diagnosis.

The Third Edition provides:

  • 800 high resolution and annotated photographs, now all fully downloadable
  • 'Key Differences' to train the eye on distinctive diagnostic features
  • Disease-based as well as alphabetical indexes
  • 75 new interactive self-assessment questions to perfect your diagnostic skills
  • Brand new algorithms for pattern analysis

Dermatopathology: Diagnosis by First Impression, Third Edition, once again provides simple and effective guidance to help you approach dermatopathology and accurate diagnosis of skin disease.

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Table of Contents

Preface, vi

Acknowledgments, vii

About the Companion Website, viii

Introduction, 1

Chapter 1 Shape on Low Power, 23


Regular acanthosis, 25

Lobular proliferation, 29

Reticulated proliferation, 35

Central pore, 42

Epidermal perforation, 46


Circular islands, 49

Cords/tubules and comma shapes, 53

Space with a lining, 59

Papillations, 70

Polypoid (dome-shaped), 77

Square/rectangular, 82

Palisading reactions, 88

Pseudoepitheliomatous hyperplasia above abscesses, 93

Pink ball, (see Chapter 6)

Chapter 2 Gestalt: Rash/inflammatory, 97

Epidermal changes

Parakeratosis, 99

Spongiosis, 102

Papulosquamous (psoriasiform), 106

Interface (vacuolar), 112

Interface (lichenoid), 117

Inflammation: Specific patterns and Cell Type Epidermal eosinophils, 123

Perivascular, 127

Band-like dermal/papillary dermal infiltrate, 131

Diffuse/nodular, 137

Subcutaneous, 144

Chapter 3 Cell Type, 153

Melanocytic, 155

Spindle cells, 164

Endothelial, 178

Giant, 192

Clear, 202

Chapter 4 “Top-Down”, 219

Hyperkeratosis/parakeratosis, 221

Upper epidermal change, 228

Acantholysis, 238

Subepidermal space/cleft, 248

Granular “material” in cells, 255

“Busy” dermis, 260

Dermal material, 263

Fat necrosis, 276

Chapter 5 Color – Blue, 279

Blue tumor, 281

Mucin and glands or ducts, 291

Mucin, 295

Chapter 6 Color – Pink, 303

Pink ball of spindle cells, 305

Pink material, 308

Pink dermis, 315

Epidermal necrosis, 317

Index (Pattern), 323

Index (Histological Category), 329

Index (Alphabetical), 333

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Author Information

Christine J. Ko is a Professor of Dermatology and Pathology at Yale University School of Medicine. She trained in dermatology at University of California, Irvine, where she was strongly influenced by Dr. Barr. She subsequently completed a fellowship in dermatopathology under Dr. Scott Binder at University of California, Los Angeles. She lectures nationally and internationally; and has published numerous book chapters, journal articles, and five textbooks/atlases in the fields of dermatology and dermatopathology.
Ronald J. Barr is Professor Emeritus of Dermatology and Pathology at the University of California, Irvine. He is a nationally and internationally recognized dermatopathologist with board certification in dermatology, anatomic pathology, and dermatopathology. He received the Founders' Award from the American Society of Dermatopathology for his myriad contributions to the field of dermatopathology and the Society's Walter Nickel Award for excellence in teaching dermatopathology. He has authored over 150 original articles and book chapters. He is also past president of the American Society of Dermatopathology and past president of the American Board of Dermatology.
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Students Resources
Wiley Student Companion Site
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