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Mitochondrial Dysfunction by Drug and Environmental Toxicants, Two Volume Set

ISBN: 978-1-119-32970-1
800 pages
February 2018
Mitochondrial Dysfunction by Drug and Environmental Toxicants, Two Volume Set (1119329701) cover image

Description

Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.

•    Covers both basic science and applied technology / methods
•    Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
•    Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
•    Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
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Author Information

Yvonne Will, PhD, is a Senior Director and the Head of Science and Technology Strategy, Drug Safety Research and Development at Pfizer, Connecticut, USA. In addition to the prior edition of this book, she co-edited Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers(Wiley, 2016).

James A. Dykens, PhD, oversees EyeCyte Therapeutics, a start-up developing treatments for progressive blinding diseases via targeting mitochondrial dysfunction. He co-edited the first edition of this book.
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