Introduction to Strategies for Organic Synthesis, 2nd Edition
Bridging the Gap Between Organic Chemistry Fundamentals and Advanced Synthesis Problems
Introduction to Strategies of Organic Synthesis bridges the knowledge gap between sophomore-level organic chemistry and senior-level or graduate-level synthesis to help students more easily adjust to a synthetic chemistry mindset. Beginning with a thorough review of reagents, functional groups, and their reactions, this book prepares students to progress into advanced synthetic strategies. Major reactions are presented from a mechanistic perspective and then again from a synthetic chemist’s point of view to help students shift their thought patterns and teach them how to imagine the series of reactions needed to reach a desired target molecule.
Success in organic synthesis requires not only familiarity with common reagents and functional group interconversions, but also a deep understanding of functional group behavior and reactivity. This book provides clear explanations of such reactivities and explicitly teaches students how to make logical disconnections of a target molecule.
This new Second Edition of Introduction to Strategies for Organic Synthesis:
- Reviews fundamental organic chemistry concepts including functional group transformations, reagents, stereochemistry, and mechanisms
- Explores advanced topics including protective groups, synthetic equivalents, and transition-metal mediated coupling reactions
- Helps students envision forward reactions and backwards disconnections as a matter of routine
- Gives students confidence in performing retrosynthetic analyses of target molecules Includes fully-worked examples, literature-based problems, and over 450 chapter problems with detailed solutions
- Provides clear explanations in easy-to-follow, student-friendly language
- Focuses on the strategies of organic synthesis rather than a catalogue of reactions and modern reagents
The prospect of organic synthesis can be daunting at the outset, but this book serves as a useful stepping stone to refresh existing knowledge of organic chemistry while introducing the general strategies of synthesis. Useful as both a textbook and a bench reference, this text provides value to graduate and advanced undergraduate students alike.
Laurie S. Starkey, PhD, is a Full Professor of Organic Chemistry at California State Polytechnic University, Pomona, where she has been teaching organic chemistry and organic synthesis since 1996. Her research focuses on chemical education, including the development and assessment of online learning tools and the creation of educational videos and animations. Dr. Starkey was awarded the Cal Poly Pomona College of Science’s Distinguished Teaching Award in 2000, and the Provost’s Award in Teaching Excellence in 2013.