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Structure and Reactivity in Organic Chemistry

Mark G. Moloney (Editor)
ISBN: 978-1-4051-1451-6
318 pages
April 2008, Wiley-Blackwell
Structure and Reactivity in Organic Chemistry (1405114517) cover image


The jump from an understanding of organic chemistry at lower undergraduate level to that required at postgraduate level or in industry can be difficult. Many advanced textbooks contain a level of detail which can obscure the essential mechanistic framework that unites the huge range of facts of organic chemistry. Understanding this underlying order is essential in any advanced study or application of organic chemistry. Structure and Reactivity in Organic Chemistry aims to bridge that gap.

The text opens with a short overview of the way chemists understand chemical structure, and how that understanding is essential in developing a good knowledge of chemical reactivity and mechanism. The remainder of the text presents a mechanistic classification of modern organic chemistry, developed in the context of synthetic organic chemistry and exemplified by reference to stereoselective synthesis and protecting group chemistry. This approach is intended to illustrate the importance and value of a good grasp of organic reaction mechanisms, which is a prerequisite for a broader understanding of organic chemistry.

Written by an expert educator with a sound understanding of the needs of different audiences, the subject is presented with clarity and precision, and in a highly practical manner. It is relevant to undergraduates, postgraduates and industrial organic chemists.

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Table of Contents

1. Bonding.

2. Structure.

3. Reactivity.

4. Intermediates.

5. Acidity and Basicity.

6. Nucleophilic Substitution.

7. Addition Reactions.

8. Elimination Reactions.

9. Aromatic Substitution.

10. Sequential Addition and Elimination Reactions.

11. Radical Reactions.

12. Ligand Coupling Reactions.

13. Pericyclic Reactions

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Author Information

Mark G. Moloney
Chemistry Research Laboratory, University of Oxford and St Peter’s College, Oxford.
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The Wiley Advantage

  • Written by an expert educator with a sound understanding of the needs of undergraduate, postgraduate and industrial organic chemists. The subject is covered with the clarity and precision necessary to enable the student to understand the material with the minimum of distraction.
  • Contains many examples of the application of mechanistic principles in synthetic organic chemistry, ensuring the undergraduate student understands how chemists apply their understanding of reaction mechanism in the development of new synthetic methods
  • Bridges the gap between standard undergraduate textbooks, which generally take a functional group approach to chemistry, and advanced level textbooks, which often obscure the really fundamental information in the level of detail they present.
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“The author's approach is methodical and clever in that he brings relevance to protecting group chemistry under each class of reactions.” (CHOICE)

"It will serve as a good reference source for any course that deals with physical organic chemistry." (CHOICE, January 2009)

"An extremely well thought out and well presented book that achieves the author’s stated aims and deserves to be on any practising organic chemist’s shelf." (The Higher Education Academy Physical Sciences Centre, December 2008)

"This book will be extremely useful as a guide to the essentials of modern organic chemistry, provided that you have a very good knowledge of organic chemistry or an excellent teacher to guide you through it." (Angewandte Chemie International Edition, December 22, 2008)

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Structure and Reactivity in Organic Chemistry (US $66.00)

-and- Reaction Mechanisms At a Glance: A Stepwise Approach to Problem-Solving in Organic Chemistry (US $49.00)

Total List Price: US $115.00
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