1 Endothelial functions and dysfunctions.

Raffaele De Caterina, Marika Massaro, & Peter Libby.

2 Endothelial activation and the initiation of atherosclerosis.

Raffaele De Caterina, Antonella Zampolli, Guido Lazzerini, & Peter Libby.

3 Mechanisms of plaque progression and complications.

Raffaele De Caterina, Antonella Zampolli, Serena Del Turco, & Peter Libby.

4 Angiogenesis in cardiovascular disease.

Karen S. Moulton.

Part II The endothelium and cardiovascular risk factors.

5 VLDL and atherosclerosis.

Jan Nilsson, Mikko P.S. Ares, & Wolfgang Dichtl.

6 High-density lipoprotein and atheroprotection.

Brian Krause, Reynold Homan, & Roger Newton.

7 Advanced glycation endproducts and the accelerated atherosclerosis in diabetes.

Giuseppina Basta, Ann Marie Schmidt, & Raffaele De Caterina.

8 Homocysteine and endothelial dysfunction.

Rosalinda Madonna & Raffaele De Caterina.

9 Lipoprotein(a) and the artery wall.

Angelo M. Scanu & Marilena Formato.

10 Oxidative stress and vascular disease.

Dominik Behrendt & Peter Ganz.

11 Infections and vascular disease.

Amir Kol & Peter Libby.

Part III Diagnostic tools and markers of endothelial functions.

12 Endothelial vasodilatory dysfunction: basic concepts and practical implementation.

Scott Kinlay & Peter Ganz.

13 Endothelial vasodilatory dysfunction and risk factors in adults.

Mark R. Adams & David S. Celermajer.

14 Endothelial vasodilatory dysfunction in early life.

Julian P.J. Halcox & John E. Deanfield.

15 Endothelial vasodilatory dysfunction in hypertension.

Umberto Campia & Julio A. Panza.

16 Vascular function and diabetes mellitus.

Mark A. Creager & Joshua A. Beckman.

17 Dyslipidemia and endothelial dysfunction: pathophysiology and therapy.

Todd J. Anderson & Francois Charbonneau.

18 Soluble adhesion molecules as in vivo biohumoral markers of vascular cell activation.

Jacopo Gianetti & Raffaele De Caterina.

Part IV Endothelium-directed prevention and therapy.

19 Hormone replacement therapy and cardiovascular disease.

Tommaso Simoncini.

20 Anti-atherogenic effects of omega-3 fatty acids.

Antonella Zampolli, Erling Falk, & Raffaele De Caterina.

21 Treatment of endothelial dysfunction and atherosclerosis by cholesterol lowering.

Masanori Aikawa & Peter Libby.

22 Antioxidants and endothelial protection.

Domenico Praticò.

23 Angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers to reverse endothelial dysfunction.

G.B. John Mancini & Sammy Y. Chan.

24 PPARs in atherosclerosis.

Ouliana Ziouzenkova, Nikolaus Marx, Peter Libby & Jorge Plutzky.

25 Stem cells in atherosclerosis and atherosclerosis-related vascular disorders.

Yong-Jian Geng & Rosalinda Madonna.

26 Endothelium-targeted gene and cell-based therapy for cardiovascular disease.

Luis G.Melo, Alok S. Pachori, Deling Kong, Massimiliano Gnecchi, & Victor J. Dzau.

Index