Preface.

Section one: Epidemiology.

1 Epidemiology of non-ST-segment elevation acute coronary syndromes.

David Hasdai and Alexander Battler.

Section two: Pathophysiology.

2 Pathologic findings in acute coronary syndromes.

Erling Falk.

3 Vascular biology of acute coronary syndromes.

Lina Badimon.

Section three: Clinical aspects of ACS.

4 Clinical aspects of acute coronary syndromes.

Eugene McFadden.

5 Circulating biomarkers for risk stratification.

Christopher Heeschen.

Section four: Investigation in ACS.

6 Coronary angiography, angioscopy, and intravascular ultrasound in non-ST segment elevation acute coronary syndromes.

Eric Van Belle, Christophe Bauters, François Schiele, and Michel E. Bertrand.

7 New coronary imaging in acute coronary syndrome.

Pim J. de Feyter, Evelyne Regar, and Nico R.A. Mollet.

Section five: Special groups of patients.

8 Acute coronary syndromes in special groups of patients.

Piero O. Bonetti, Michael J. Zellweger, Christoph Kaiser, and Matthias E. Pfisterer.

Section six: Pharmacological treatment.

9 Antiischemic treatment (nitrates, β-blockers, calcium antagonists).

David McCarty, Colum G. Owens, and A.A. Jennifer Adgey.

10 Antiplatelet therapies: aspirin, thienopyridines, and glycoprotein IIb/IIIa receptor inhibitors.

Jaydeep Sarma and Keith A.A. Fox.

11 Antithrombin drugs: LMWH, unfractionated heparin, direct thrombin inhibitors .

Raphaelle Dumaine and Gilles Montalescot.

12 Statin therapy in ACS.

François Schiele.

Section seven: Myocardial revascularization.

13 Percutaneouscoronary interventionsand stenting/CABG in non-ST-segment elevation acute coronary syndromes.

Nicolas Meneveau and Jean-Pierre Bassand.

Section eight: Therapeutic strategy.

14 Risk stratification and therapeutic strategy.

Christian W. Hamm.

15 Indication for revascularization in non-ST-elevation acute coronary syndrome.

Lars Wallentin.

16 Management of patientswith nonamenable lesions for myocardial revascularization.

Victor Legrand.

17 Non-ST-segment elevation coronary syndromes: European Society of Cardiology guidelines.

Michel E. Bertrand.

18 Non-ST-segment elevation acute coronary syndromes: ACC/AHA guidelines.

Pierre Théroux.

19 From guidelines to registries.

Luigi Tavazzi.

Section nine: Secondary prevention.

20 Secondary prevention after acute episode of patients presenting with nonpersistent ST-segment elevation.

Michel E. Bertrand.

21 How to detect vulnerable plaque.

Dirk Boese and Raimund Erbel.

22 Local versus systemic prevention treatment.

Mario Togni and Bernhard Meier.

Conclusions.

Index