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Evidence-Based Nephrology

ISBN: 978-1-4051-3975-5
864 pages
December 2008, BMJ Books
Evidence-Based Nephrology (1405139757) cover image
This book covers the management of all major renal diseases from an evidence-based and patient-centred approach. With contributions from leading international experts who have a real understanding of evidence-based medicine it provides recommendations on treatment regimens to adopt for individual patients that are most strongly supported by the evidence.

The inclusion of the latest observational and epidemiological data, as well as randomized controlled trial evidence ensures that the book properly reflects the current state of evidence available for nephrological practice. It will be a useful aid to all clinicians, including those caring for transplant and pediatric patients, as it covers the major clinical questions encountered by nephrologists.

This reference is an invaluable source of evidence-based information distilled into guidance for clinical practice which will be welcomed by practitioners, trainees and associated health professionals.

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1 Epidemiology of chronic kidney disease.

William M. McClellan & Friedrich K. Port .

2 Chronic disease surveillance and chronic kidney disease.

Diane L. Frankenfield & Michael V. Rocco .

3 Risk factors for progression of chronic kidney disease.

Eberhard Ritz, Danilo Fliser & Marcin Adamczak.

4 Epidemiology and screening for chronic kidney disease.

Sylvia Paz B. Ramirez .

5 Prediction of risk and prognosis: decision support for diagnosis and management of chronic kidney disease.

Benedicte Stengel, Marc Friossart & Jerome Rossert .


6 Definition, classification, and epidemiology of acute kidney injury.

Eric A. J. Hoste, Ramesh Venkatamaran, & John A. Kellum .

7 Pre-renal failure and obstructive diseases.

Kevin W. Finkel .

8 Hepatorenal syndrome.

Andrés Cárdenas & Pere Ginès.

9 Acute tubular necrosis.

Jay L. Koyner & Patrick T. Murray.

10 Radiocontrast nephropathy.

Brendan J. Barrett & Patrick S. Parfrey .

11 Miscellaneous etiologies of acute kidney injury.

Kamalanathan K. Sambandam & Anitha Vijayan .

12 Renal replacement therapy in acute kidney injury.

Steven D. Weisbord & Paul M. Palevsky .


13 Management of idiopathic nephrotic syndrome in adults: Minimal change disease and focal segmental glomerulosclerosis.

Alain Meyrier .

14 Membranous nephropathy.

Fernando C. Fervenza & Daniel C. Cattran .

15 IgA nephropathy in adults and children.

Jonathan Barratt, John Feehally & Ronald Hogg .

16 Membranoproliferative glomerulonephritis.

Richard J. Glassock .


Hypertensive renal disease.

17 Hypertension: classification and diagnosis.

Bernardo Rodriguez-Iturbe & Crispin Marin Villalobos .

18 Management of essential hypertension.

Eberhard Ritz, Danilo Fliser & Marcin Adamczak .

19 Management of hypertension in chronic kidney disease.

Aimun Ahmed, Fairol H. Ibrahim & Meguid El Nahas .

20 Diagnosis and management of renovascular disease.

Jörg Radermacher .

21 Diabetes mellitus.

Piero Ruggenenti & Giuseppe Remuzzi .

22 Lupus nephritis.

Arrigo Schieppati, Erica Daina & Giuseppe Remuzzi .

23 Infection-related nephropathies.

Monique E. Cho & Jeffrey B. Kopp .

24 Hepatitis B virus.

M. Aamire Ali, Scott D. Cohen & Paul L. Kimmel .

25 Infection-related nephropathies: Hepatitis C virus.

Dirk R. J. Kuypers .

26 Polyomavirus-associated nephropathy.

Fabrizio Gievri & Hans H. Hirsch.

Toxic nephropathies.

27 Toxic nephropathies: Nonsteroidal anti-inflammatory drugs.

Wai Y. Tse & Dwomoa Adu.

28 Toxic nephropathies: Environmental agents and metals.

Richard P. Wedeen .

29 The kidney in pregnancy.

Phyllis August & Tiina Podymow .


30 Progression of chronic kidney disease: diagnosis and management.

Anil K. Agarwal, Nabil Haddad & Lee A. Hebert .

31 Treatment of anemia in chronic kidney disease, stage 3-5.

Robert N. Foley .

32 Dyslipidemia in chronic kidney disease.

Vera Krane & Christoph Wanner .

33 Chronic kidney disease and hypertension.

Sangeetha Satyan & Rajiv Agarwal .

34 Recognition and management of mineral and bone disorder of chronic kidney disease and end-stage renal disease.

Donald A. Maloney.

35 Preparation for dialysis.

Mark G. Parker & Jonathan Himmelfarb .


36 When to start dialysis and whether the first treatment should be an extracorporeal therapy or peritoneal dialysis.

Raymond T. Krediet .

37 Modalities of extracorporeal therapy: hemodialysis, hemofiltration and hemodiafiltration.

Kannaiyan S. Rabindranath & Norman Muirhead .

38 Dialysis delivery and adequacy.

Peter Kotanko, Nathan W. Levin & Frank Gotch .

39 General management of the hemodialysis patient.

Robert Mactier & David C. Wheeler .

40 Infections in hemodialysis.

Behdad Afzali & David J.A Goldsmith .

41 Non-access-related nosocomial infections in hemodialysis.

Brett W. Stephens & Donald A. Molony .

42 Vascular access for hemodialysis.

Kevan R. Polkinghorne .


43 Selection of peritoneal dialysis as renal replacement therapy.

Norbert Lameire, Raymond Vanholder & Wim Van Biesen .

44 Small solute clearances in peritoneal dialysis as renal replacement therapy.

Sharon J. Nessim & Joanne M. Bargman .

45 Salt and water balance in peritoneal dialysis.

Cheuk-Chun Szeto & Philip Kam-Tao Li .

46 Impact of peritoneal dialysis solutions on outcomes.

David W. Johnson & John D. Williams .

47 Prevention and treatment of peritoneal dialysis-related infections.

Giovanni F. M. Strippoli, Kathryn J. Wiggins, David W. Johnson, Sankar Navaneethan, Giovanni Cancarini & Jonathan C. Craig .



48 Evaluation and selection of the kidney transplant candidate.

Bryce Kiberd .

49 Evaluation and selection of the living kidney donor.

Connie L. Davis .

50 Predictors of transplant outcomes.

Krista L. Lentine, Robert M. Perkins & Kevin C. Abbott .

51 The early course: induction, delayed function, and rejection.

Paul A. Keown .

52 Maintenance immunosuppression therapy.

Yves Vanrenterghem .

53 Chronic allograft nephropathy.

Bengt C. Fellström, Alan Jardine & Hallvard Holdaas .


54 Overview of electrolyte and acid-base disorders.

L. Lee Hamm & Michael Haderlie .

55 Hyponatremia.

Chukwuma Eze & Eric E. Simon .

56 Potassium disorders.

John R. Foringer, Christopher Norris & Kevin W. Finkel .

57 Metabolic evaluation and prevention of renal stone disease.

David S. Goldfarb .


Themes across renal disease and renal failure.

58 Growth, nutrition, and pubertal development.

Lesley Rees.

59 Hypertension, cardiovascular disease, and lipid abnormalities in children with chronic kidney failure.

Elke Wühl & Franz Schaefer .

60 Bones across kidney disease and kidney failure.

Mary B. Leonard .

61 Anemia.

Susan Furth & Sandra Amaral .

Management of renal failure/transplants.

62 Renal transplantation.

Pierre Cochat & Justine Bacchetta .

63 Peritoneal dialysis in children.

Jaap W. Groothoff & Maruschka P. Merkus .

64 Pediatric hemodialysis.

Stuart L. Goldstein.

Specific pediatric renal disease.

65 Urinary tract infection, vesicoureteric reflux and urinary incontinence.

Gabrielle Williams, Premala Sureshkumar, Patrina Caldwell & Jonathan C. Craig.

66 Epidemiology and general management of childhood idiopathic nephrotic syndrome.

Nicholas J. A. Webb .

67 Management of steroid-sensitive nephrotic syndrome.

Elisabeth M. Hodson, Jonathan C. Craig & Narelle S. Willis.

68 Steroid-resistant nephrotic syndrome.

Annabelle Chua & Peter Yorgin.

Other pediatric renal diseases .

69 Henoch-Schonlein nephritis and membranoproliferative glomerulonephristis.

Sharon Phillips Andreoli .

70 Cystinosis.

William C. van't Hoff

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Donald Molony MD

Internal Medicine, Division of Renal Disease and Hypertension and Center for Clinical Research and Evidence-based Medicine, University of Texas-Houston Medical School, Houston, TX, USA

Jonathan C. Craig MD, PhD, FRACP

Department of Nephrology and Centre for Kidney Research, NHMRC Centre for Clinical Research Excellence in Renal Medicine, The Children’s Hospital at Westmead, and School of Public Health, University of Sydney, Australia

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  • An important and unique new renal medicine text for nephrologists
  • Makes the best evidence for treatment readily and easily available to the clinician
  • Covers management of all the major renal diseases
  • Written and edited by leading experts in nephrology and evidence-based medicine, many from the Cochrane Collaboration
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“Throughout, tables, diagrams, and other illustrations provide clinical and laboratory correlates for the different facets of nephrology. The book provides a unique and comprehensive review of commonly encountered topics encountered by the nephrologist.” (JAMA, May 2010)

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