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Surgical Management of Vitiligo

Somesh Gupta (Editor), Mats J. Olsson (Editor), Amrinder J. Kanwar (Editor), Jean-Paul Ortonne (Editor)
ISBN: 978-1-4051-4521-3
304 pages
November 2006, Wiley-Blackwell
Surgical Management of Vitiligo (1405145218) cover image

Description

Although vitiligo has traditionally been very difficult to treat, a new breakthrough surgical treatment is expanding options for practitioners and patients.

Standard treatments depend on the severity of the condition and the patient's feelings of disfigurement. Cover-up cosmetics work well for some people. Other more sophisticated forms of treatment include gradually developing color back in the depigmented areas (repigmentation) by PUVA or other ultraviolet light treatments, but this is extremely slow and intensive, often requiring several hundred treatments.

This new form of treatment, which involves surgically transplanting melanocytes into the white areas, is most successful in patients with stable vitiligo over less than 30% of their body surface area. It complements medical therapies in achieving complete and sustained repigmentation and is rapidly gaining popularity in all major centers.

This is the first book available which describes this major advance in detail.


  • Explains the new treatment of surgically transplanting melanocytes into the affected areas of the skin to provide dermatologists and surgeons with the latest state-of-the-art information

  • Written by the international leaders who pioneered this treatment

  • Presents all the latest information on the topic, eliminating the need to search through multiple sources for specific data
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Table of Contents

Section 1 Pathogenesis and Medical Treatment.

1 Pathogenesis of Vitiligo. (Jean-Paul Ortonne).

2 Understanding the Mechanism of Repigmentation in Vitiligo. (Amrinder J. Kanwar and Davinder Parsad).

3 Classification of Vitiligo. (Sang Ju Lee, Sung Bin Cho and Seung-Kyung Hann).

4 Medical Treatment of Vitiligo. (Thierry Passeron and Jean-Paul Ortonne).

Section 2 Overview of Surgical Management.

5 History and chronology of development of surgical therapies for vitiligo. (Rafael Falabella).

6 The Concept of Stability of Vitiligo. (Koushik Lahiri and Subrata Malakar).

7 Patient Selection and Preoperative Information in Surgical Therapies for Vitiligo. (Nanny van Geel and Jean Marie Naeyaert).

8 Classification of Surgical Therapies for Vitiligo. (Philippe Bahadoran and Jean-Paul Ortonne).

9 Surgical Management of Vitiligo and Other Leukodermas: Evidence-based Practice Guidelines. (Somesh Gupta, Tarun Narang, Mats J. Olsson and Jean-Paul Ortonne).

10 Evaluation of Outcome in Surgical Therapies for Vitiligo. (Nanny van Geel and Jean Marie Naeyaert).

Section 3 Tissue Grafting.

11 Minigrafting for Vitiligo. (Subrata Malakar and Koushik Lahiri).

12 Suction Blister Epidermal Grafting. (Somesh Gupta and Ashima Goel).

13 Thin Split-thickness Skin Grafts for Vitiligo. (Niti Khunger).

14 Treatment of Leukoderma by Transplantation of Ultra-thin Epidermal Sheets. (Mats J. Olsson).

15 Transplantation of Hair Follicles for Vitiligo. (Subrata Malakar, Gun Yoen Na and Koushik Lahiri).

16 Mesh Grafts for Vitiligo. (C.R. Srinivas, Reena Rai and M. Sinha).

17 Flip-top Pigment Transplantation. (Brent E. Pennington, Jean L. Bolognia and David J. Leffell).

18 Ultrasonic Abrasion and Seed Grafts for Vitiligo. (Katsuhiko Tsukamoto, Reiko Kitamura and Osami Takayama).

19 Complications and Limitations of Melanocyte Transplantation. (Yvon Gauthier).

Section 4 Cellular Grafting.

20 Treatment of Leukoderma by Transplantation of Basal Cell Layer Suspension. (Mats J. Olsson).

21 Setting up a Tissue Culture Laboratory. (Rafal Czajkowski, Tomasz Drewa and Waldemar Placek).

22 Treatment of Leukoderma by Transplantation of Cultured Autologous. Melanocytes (Mats J. Olsson).

23 Transplantation of in Vitro Cultured Epithelial Grafts for Vitiligo and Piebaldism. (Liliana Guerra, Sergio Bondanza and Desanka Raskovic).

24 Simplifying the Delivery of Cultured Melanocytes and Keratinocytes for Grafting Patients with Vitiligo. (Sheila MacNeil and Paula Eves).

25 Safety Concerns in Transplantation of in Vitro Cultured Cellular Grafts. (Liliana Guerra, Elena Dellambra and Patrizia Paterna).

Section 5 Special Issues.

26 Post-surgery Patient Information. (Mats J. Olsson).

27 Surgical Management of Lip Vitiligo. (Somesh Gupta, Ashima Goel and Amrinder J. Kanwar).

28 Surgical Management of Vitiligo of Eyelids and Genitals: Special Issues. (Somesh Gupta).

29 Surgical Management of Acral vitiligo. (Sharad Mutalik).

30 Surgical Management of Leukotrichia. (Karoon Agrawal and Aparna Agrawal).

31 Surgical Treatments of Leukodermas other than Vitiligo Vulgaris. (Mats J. Olsson).

Section 6 Miscellaneous.

32 Micropigmentation. (Gurvinder P. Thami).

33 Laser for Repigmenting Vitiligo. (Thierry Passeron and Jean-Paul Ortonne).

34 Application of Lasers in Transplantation Procedures for Vitiligo. (Cengiz Acikel, Ersin Ulkur and Bahattin Celikoz).

35 Combining Medical and Surgical Therapies. (Alain Taïeb and Yvon Gauthier).

36 Surgical Depigmentation of Vitiligo: Bleaching Cream, Laser and Cryosurgery. (Monique R.T.M. Thissen).

37 Future directions in Surgical Management of Vitiligo. (Yvon Gauthier).

38 Informed Consent. (Mats J. Olsson)

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Author Information

Somesh Gupta, MD, DNB
Department of Dermatology and Venereology
All India Institute of Medical Sciences
New Delhi, India

Mats J. Olsson, PhD
Department of Medical Sciences
Section of Dermatology and Venereology
University Hospital
Uppsala, Sweden

Amrinder J. Kanwar, MD
Department of Dermatology, Venereology and Leprology
Postgraduate Institute of Medical Education and Research
Chandigarh, India

Jean-Paul Ortonne, MD
Department of Dermatology
Nice University Hospital
Nice, France

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The Wiley Advantage

The first comprehensive reference on the surgical treatment of vitiligo


  • Explains the new treatment of surgically transplanting melanocytes into the affected areas of the skin to provide dermatologists and surgeons with the latest state-of-the-art information
  • Written by the international leaders who pioneered this treatment
  • Presents all the latest information on the topic, eliminating the need to search through multiple sources for specific data
See More

Reviews

"This is a comprehensive monograph on all the current and some possible new ways to transplant autologous melanocytes from areas of pigmented skin to areas of leukoderma in patients with vitiligo and several other forms of leukoderma...

... it should be in the library of all those involved in this type therapy. It will expand the surgical armamentarium of those with interests in the surgical management of vitiligo."

- James J. Nordlund, MD Dayton, Ohio(J AM ACAD DERMATOL) VOLUME 57, NUMBER 6


"...this is a wonderfully comprehensive textbook and is a bargain as well. Because most dermatologic surgeons see pigmentary disorders...this book would make a nice addition to libraries."
Dermatological Surgery

“A welcome surprise…a comprehensive monograph on all the current and new ways to transplant…should be in the library of all those involved in this therapy.”
Journal of the American Medical Association

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