Foreword.

Preface.

Part 1: Gastrointestinal Diseases and Disorders: The Public Health.

Perspective.

1 The Importance of GI Epidemiology: G. Richard Locke III (Mayo Clinic College of Medicine) and Nicholas J. Talley (Mayo Clinic College of Medicine).

2 The Burden of Gastrointestinal and Liver Diseases: Nicholas J. Shaheen.

Part 2: Methodological Issues in GI Epidemiology.

3 Overview of Epidemiologic Methodology: L. Joseph Melton III and Steven J. Jacobsen.

4 Patient-Reported Outcomes: Ingela Wiklund.

5 GI Questionnaires: G. Richard Locke III (Mayo Clinic College of Medicine).

6 Clinical Trials: William J. Sandborn.

7 Decision Analysis: John M. Inadomi.

8 Health Economics: Dawn Provenzale and Joseph Lipscomb.

9 Systematic Reviews: Philip Schoenfeld.

10 Meta-analyses: Paul Moayyedi.

11 Large Databases for Epidemiologic Studies: Jessica A. Davila and Hashem B. El-Serag.

12 Nutritional Epidemiology: Linda E. Kelemen.

13 Infection Epidemiology and Acute Gastrointestinal Infections: Sarah J. O’Brien and Smita L.S. Halder.

14 Genetic Epidemiology: Yuri A. Saito (Miles and Shirley Fiterman Center for Digestive Diseases) and Gloria M. Petersen.

15 A Career in GI Epidemiology: Linda Rabeneck.

16 Funding Opportunities at the National Institutes of Health: James E. Everhart and Judith M. Podskalny.

Part 3: Epidemiology of Specific GI Diseases.

17 GERD, Barrett’s Esophagus and Esophageal Cancer: Yvonne Romero and G. Richard Locke III (Mayo Clinic College of Medicine).

18 Helicobacter pylori Infection, Peptic Ulcer Disease and Gastric Cancer: Olof Nyrén.

19 Dyspepsia: Nimish B. Vakil and Nicholas J. Talley (Mayo Clinic College of Medicine).

20 Upper Gastrointestinal Bleeding: James Lau and Joseph Sung.

21 Celiac Disease: Alberto Rubio-Tapia and Joseph A. Murray.

22 Measuring Utilization of Colonoscopy in Clinical Practice: David Lieberman.

23 Colorectal Carcinoma: Steven B. Ingle and Paul Limburg.

24 Irritable Bowel Syndrome: Yuri A. Saito (Miles and Shirley Fiterman Center for Digestive Diseases) and Nicholas J. Talley (Mayo Clinic College of Medicine) and G. Richard Locke III (Mayo Clinic College of Medicine).

25 Constipation: John F. Johanson.

26 Infectious Diarrhea: Crenguta Stepan and Christina M. Surawicz.

27 Inflammatory Bowel Disease: Edward V. Loftus Jr.

28 Fecal Incontinence: Adil E. Bharucha.

29 Gallstones: Torben Jørgensen.

30 Pancreatitis: Santhi Swaroop Vege and Dhiraj Yadav and Suresh T. Chari.

31 Pancreatic Cancer: Suresh T. Chari.

32 Alcoholic Liver Disease: Mary C. Dufour.

33 Cirrhosis and Hepatocellular Carcinoma: William Sanchez and Jayant A. Talwalkar.

34 Nonalcoholic Fatty Liver Disease: Paul Angulo.

35 Hepatitis B and C: W. Ray Kim.

Index