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ABC of Transfusion, 4th Edition

ISBN: 978-1-4051-5646-2
128 pages
April 2009, BMJ Books
ABC of Transfusion, 4th Edition (1405156465) cover image


Blood services and Transfusion Medicine have become more clinical, scientific, well organised and consolidated over the last 20 years. More is known about the frequency and aetiology of the hazards of blood transfusions. The ABC of Transfusion is a well established introduction for all staff working in blood services, blood transfusion departments, surgical units and intensive care, and all prescribers and users of blood. It is a comprehensive, highly regarded guide to all the practical aspects of blood transfusion, including the various complications that can arise.

This fourth edition of ABC of Transfusion includes five new chapters on all the latest issues including pre-transfusion testing, vCJD, stem cell transplantation, immunotherapy, and appropriate use of blood - reflecting the fact that transfusion medicine has been revolutionised.

Useful as a practical guide, a refresher or for quick reference, it covers all essential transfusion matters and is an ideal source of information for all health professionals involved with safe and efficient use of blood.

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Table of Contents

Contributors, v

Introduction, vii

1 The Blood Donor: Demographics, Donor Selection and Tests on Donor Blood, 1
Liz Caffrey, Patricia Hewitt and John Barbara

2 Supply and Demand for Blood and Blood Components and Stock Management, 6
Judith Chapman, Peter Garwood and Sue Knowles

3 Compatibility Testing Before Transfusion; Blood Ordering and Administration, 10
Marcela Contreras and Aleksandar Mijovic

4 Red Cell Transfusion, 15
Mike Murphy and Jonathan Wallis

5 Platelet and Granulocyte Transfusions, 22
Modupe Elebute, Simon Stanworth and Cristina Navarrete

6 Haemolytic Disease of the Newborn and its Prevention, 27
Fiona Regan, Sailesh Kumar and Marcela Contreras

7 Fetal and Neonatal Transfusion, 33
Helen V. New and Sailesh Kumar

8 Plasma Products and Indications for Their Use, 40
Hannah Cohen and Trevor Baglin

9 Human Albumin Solutions and the Controversy of Crystalloids Versus Colloids , 48
Neil Soni

10 Treatment of Massive Haemorrhage in Surgery and Trauma, 54
Tim Walsh

11 Immunological Complications of Blood Transfusion, 61
Marcela Contreras and Cristina Navarrete

12 Infectious Complications of Blood Transfusion: Bacteria and Parasites, 69
John Barbara and Marcela Contreras

13 Infectious Complications of Blood Transfusion: Viruses, 74
John Barbara and Marcela Contreras

14 Variant Creutzfeldt–Jakob Disease and its Impact on the UK Blood Supply, 79
Patricia Hewitt, James Ironside and Marcela Contreras

15 Risks of Transfusion in the Context of Haemovigilance: SHOT – the UK Haemovigilance System, 83
Dorothy Stainsby, Hannah Cohen and Brian McClelland

16 Alternatives to Allogeneic Blood Transfusion, 89
Dafydd Thomas and Beverley Hunt

17 Blood Substitutes and Oxygen Therapeutics, 95
Kenneth C. Lowe

18 Appropriate Use of Blood and Better Blood Transfusion, 99
Mike Murphy

19 Stem Cell Transplantation and Cellular Therapies, 104
Aleksandar Mijovic, Derwood Pamphilon and Suzanne Watt

20 Blood Transfusion in a Regulatory Environment and the EU Directives, 110
Shubha Allard, Clare Taylor and Angela Robinson

Index, 117

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Author Information

Marcela Contreras, DBE, Chairman - Blood Transfusion International; Professor of Transfusion Medicine, Royal Free and University College Hospitals Medical School, London, UK and retired National Director of Diagnostics, Development and Research, National Blood Service, London, UK
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The Wiley Advantage

A comprehensive and highly regarded guide to all the practical aspects of blood transfusion

  • New edition of an established reference from a leading centre in transfusion
  • Includes five new chapters on variant CJD, stem cell transplantation, immunotherapy, blood matching and appropriate use of transfusion
  • Reflects the latest developments in blood transfusion management
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