Handbook of Hypertension
April 2009, Wiley-Blackwell
The Handbook of Hypertension is a comprehensive review of the evidence base for hypertension and associated disease, providing tables, figures, charts, and summaries of principal findings from clinical studies on hypertension – putting vital information within reach of the busy practitioner.
Containing the most recent guidelines for global cardiovascular risk analysis and evidence-based reviews on important new advances and recent trials, consulting the Handbook of Hypertension will save precious time and improve patient care.
General Introduction .
New Treatment Approach.
Hypothesis: Essential Hypertension and End-Organ Damage.
Hypertension Classification and Guidelines Wordwide.
Hypertension in the US.
NHANES III and IV.
Global Cardiovascular Risk Calculation.
Measurement of Blood Pressure.
Indirect measurement of blood pressure.
Common Mistakes in Blood Pressure Measurement.
Nonpharmacologic Treatment of Hypertension.
Nutraceuticals, Vitamins, Minerals and Antioxidants.
DASH I and II Trials.
Approaches to Selection of Antihypertensive Therapy.
Subsets of Hypertension.
Renin Profiling: The Laragh Method.
Hemodynamics in Hypertension.
Hemodynamics: Logical and Preferred Method to Reduce Blood Pressure.
Hemodynamic Effects of Antihypertensive Drugs.
Hypertension-Related End-Organ Damage.
Life Expectancy and Blood Pressure.
Systolic, Diastolic and Pulse Pressure Concepts.
Isolated Systolic Hypertension.
Clinical Hypertension Trials and Antihypertensive .
Drug Therapy .
Completed Trials and Trials in Progress.
Diuretic and Beta-Blocker Trials.
Summary of Clinical Trials with Diuretics.
Summary of Clinical Trials with Beta-Blockers.
Meta-Analysis of Various Clinical Trials.
Comparisons of ACE-Inhibitor therapy with Placebo.
Comparisons of Calcium-antagonist therapy with Placebo.
Comparisons of More Intensive Blood Pressure Lowering Strategies with Less.
Comparisons of Ace-Inhibitor based Therapy with Diuretic-based or Beta-Blocker Therapy.
Comparisons of Calcium-antagonist-based Therapy with Diuretic or Beta-BlockerTherapy.
Comparisons of Ace-Inhibitor Therapy with Calcium-antagonist Therapy.
Summary of Clinical Trials in Hypertension and Clinical Outcomes.
Health Outcomes Meta-Analysis.
Comparing the CCBs to other Antihypertensive Therapy.
Summary of Published Trials Involving CCBs.
Angiotensin Converting Enzyme Inhibitors (ACEI) Trials.
Summary of ACEI Trials.
Angiotensin Receptor Blockers (ARBs) Trials.
ARBs Trials Summary.
Coronary Heart Disease Risk Factor and Effects of Anti-hypertensive Drug Therapy.
Coronary Heart Disease: Risk Factors.
Coronary Heart Disease Risk Factors: More potential risk factors.
Influence of Diuretic and Beta-Blocker Therapy on CHD Risk Factors.
Antihypertensive Drugs and Serum Lipids.
Summary of Serum Lipids and Antihypertensive Therapy with Diuretics and.
Effects of Antihypertensive Drugs on Coronary Heart Disease Risk Factors.
Antihypertensive Drugs and Coronary Heart Disease Risk Factors: Summary.
Calcium Channel Blockers and Atherosclerosis (CHD Reduction Trials).
Hypertension and Renal Disease.
Classification of Chronic Kidney Disease.
Hypertension and Renal Damage.
Hypertension-Related Renal Damage:.
Is Thiazide Diuretic-Based Antihypertensive Therapy Associated with Increased.
Risk of Renal Injury.
Major Clinical Trials Showing Renoprotection.
Effects of Antihypertensive Drugs on Renal Function.
Hypertension and Diabetes Mellitus.
Hypertensive Diabetics: Mortality, Coronary Heart Disease and Antihypertensive.
BP Level Effects on Type II-DM Nephropathy.
Diabetes Mellitus and Hypertension Summary.
Selection of Therapy Based on Subsets of Hypertension.
Demographics and Antihypertensive Drugs.
Isolated Systolic Hypertension in the Elderly.
Hypertensive Urgencies and Emergencies.
Treatment; General Principles.
Treatment; Choice of Drug.
Treatment of Specific Hypertensive Disorders.
Hypertension in Pregnancy.
General Review of Antihypertensive Drug Therapy.
Quality of Life and Antihypertensive Therapy (Selected Trials).
Antihypertensive Drug Compliance.
Total Cost of Antihypertensive Therapy.
Characteristics of the Ideal Antihypertensive Drug.
Combination Antihypertensive Therapy: Selected Drugs.
Combination Antihypertensive Therapy: Selected Drugs: Summary.
Antihypertensive Therapy: Efficacy of Monotherapy.
Selected Drug Interactions with Antihypertensive Therapy.
Maximum Recommended Doses of Antihypertensive Drugs with Best Treatment Characteristics.
Specific Review of all Antihypertensive Drug Classes.
Central Alpha-Agonists: Similarities.
Central Alpha-Agonists: Highlights.
Comparison of Commonly Used Oral Central Alpha-Agonists.
Postganglionic Neuron Inhibitors.
Postganglionic Neuron Inhibitors Highlights.
Side Effects and Contraindications of Beta-Blockers.
Drug Interactions with Beta-Blockers.
Direct Vasodilators Highlights.
Angiotensin-Converting Enzyme (ACE) Inhibitors.
Renin-Angiotensin System (RAAS).
ACE Inhibitors: Highlights.
Non Hypertensive Treatment Effects of ACEIs.
Calcium Channel Blockers.
Calcium Channel Blockers: Highlights.
Treatment: Non Hypertensive Effects of CCBs.
Angiotensin II Receptor Blockers (ARBs).
Ang-II Receptor Blockers (ARBs): Highlights.
Non Hypertensive Treatment effects of ARB’s.
Serum Aldosterone Receptor Antagonists (SARA’s).
Combination of Anti-hypertensive Drug with Statin ( Amlodipine with Atorvastatin).
Arterial Compliance: Structure/Function: Treatment.
Selected Combination Antihypertensive Drugs.
Hypertension Drug Selection: Summary.
New Antihypertensive Drug Classes.
Subset Selection of Antihypertensive Therapy.
Associate Clinical Professor of Medicine
Vanderbilt University School of Medicine
ASH Specialist in Clinical Hypertension
Director, Hypertension Institute and Vascular Biology, Nashville, Tennessee
Section Chief, Division of Nutrition and Clinical Research
Staff Physician, Vascular Institute
Saint Thomas Hospital