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Tissue and Cell Processing: An Essential Guide

ISBN: 978-1-4051-9826-4
362 pages
August 2012, Wiley-Blackwell
Tissue and Cell Processing: An Essential Guide (1405198265) cover image


By presenting the latest technological advances and growing national and international regulation, this new book explores state-of-the-art developments in the challenging field of tissue and cell processing. It provides a guide to easier and safer practice in operational principles of preservation, decontamination, and sterilization. Nearly half of the book is devoted completely to tissue- or cell-specific issues relating to processing. With lists of learning points and case studies which consist of sample processing protocols, descriptions of where processing went wrong, sample risk assessments, or validation studies, the authors help you find specific information fast.
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Table of Contents

List of Contributors



1 Regulations and Standards
Michael Cox and Scott A. Brubaker

2 Risk management in Tissue & Cell Processing
Diane Wilson and Johann Kurz

3 Principles of Cell Collection and Tissue Recovery
Helen Gillan, Derwood Pamphilon, Scott A. Brubaker

4 Principles of Cell and Tissue Cryopreservation
Ying C. Song and David E. Pegg

5 Principles of tissue decontamination and sterilization
Lloyd Wolfinbarger, Jr. and Pierre Lory

6 Control of Contamination and Cross Contamination During Processing: Optimising the Processing Environment
Lisa Nair, Marisa Roma Herson and Kyle Bennett

7 The Principles of Process Validation and Equipment Qualification
Martell Winters and Richard Lomas

8 Biomechanical and Biocompatibility Testing Considerations
Caroline A Hartill

9 Coding and Traceability
Stefan Poniatowski, Izabela Uhrynowska-Tyszkiewicz and Ineke Slaper-Cortenbach

10 Training of Tissue Bank Personnel
Martí Manyalich, Debbie Butler Newman, Jacinto Sánchez Ibáñez, Aurora Navarro, Gloria Páez, & Aziz Nather

11 Cardiac Tissue: Specific Recovery and Processing Issues
Alyce Linthurst Jones, Robert Parker, Linda Manning and Helmi Albrecht

12 Skin: specific recovery and processing issues
Elisa Pianigiani and Jan L. Pierce

13 Ophthalmic tissues: recovery and processing issues
Diego Ponzin, Patricia Dahl and Elisabeth Pels

14 Skeletal Tissue: Specific Recovery and Processing Issues
Joel Osborne, Art Kurz, Esteve Trias and Oscar Fariñas

15 Processing of cells for transplantation
Mark W Lowdell & Edward Samuel

16 Gametes and embryos: specific collection and processing issues
Montserrat Boada and Anna Veiga

17 Engineering of human tissue grafts
John N. Kearney and Francisco da Costa

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Author Information

Deirdre Fehily PhD
Inspector and Technical Advisor, Tissues and Cells, National Transplant Centre, Rome, Italy

Scott A. Brubaker CTBS
Chief Policy Officer, American Association of Tissue Banks, McLean, Virginia, USA

John N. Kearney BSc, PhD, CBiol, MIBiol, SRCS
Head of Tissue Services/Lead Scientist/PI for Research, Liverpool Blood Centre, NHS Blood & Transplant, Liverpool, UK

Lloyd Wolfinbarger Jr. PhD
BioScience Consultants, llc, Norfolk, Virginia, USA

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-and- Tissue and Cell Donation: An Essential Guide (US $159.95)

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