Part I: Regional Determinants of Cell Fate:.

1. Oxygen in the Cultivation of Stem Cells. By Marie Csete.

2. DNA Damage-Induced Programmed Cell Death: Potential Roles in Germ Cell Development. By Yukiko Yamada and Clark R. Coffman.

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Part II: Intrinsic Determinants of Stem Cells:.

3. G Protein-Coupled Receptor Roles in Cell Migration and Cell Death Decisions: Angela R. Kamps and Clark R. Coffman.

4. Growth and Differentiation of Astrocytes and Neural Progenitor Cells on Micropatterned Polymer Films: Jennifer B. Recknor, D S. Sakaguchi, and S K. Mallapragada.

5. Cellular and Molecular Regulation of Hematopoietic and Intestinal Stem Cell Behavior: Xi C. He, Jiwang Zhang, and Linheng Li.

6. The Function of the Neuronal Proteins Shc and Huntingtin in Stem Cells and Neurons: Pharmacologic Exploitation for Human Brain Diseases: Chiara Zuccato, Luciano Conti, Erika Reitano, Marzia Tartari, and Elena Cattaneo.

7. Engineering a Dopaminergic Phenotype in Stem/Precursor Cells: Role of Nurr1, Glia-Derived Signals, and Wnts: Ernest Arenas.

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Part III: Transdifferentiation:.

8. Umbilical Cord Blood-Derived Stem Cells and Brain Repair: Paul R. Sanberg, Alison E. Willing, Svitlana Garbuzova-Davis, Samuel Saporta, Guoqing Liu, Cyndy Davis Sanberg, Paula C. Bickford, Stephen K. Klasko, and Nagwa S. El-Badri.

9. Infusion of Human Umbilical Cord Blood Ameliorates Neurologic Deficits in Rats with Hemorrhagic Brain Injury: Zhenhong Nan, andrew Grande, Cyndy D. Sanberg, Paul R. Sanberg, and Walter C. Low.

10. How Wnt Signaling Affects Bone Repair by Mesenchymal Stem Cells from the Bone Marrow: Carl A. Gregory, William G. Gunn, Emigdio Reyes, Angela J. Smolarz, James Munoz, Jeffrey L. Spees, and Darwin J. Prockop.

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Part IV: Stem Cell Responses to Perturbation:.

11. Human Retinal Progenitor Cells Grown as Neurospheres Demonstrate Time-Dependent Changes in Neuronal and Glial Cell Fate Potential: David M. Gamm, Aaron D. Nelson, and Clive N. Svendsen.

12. Neural Progenitor Cell Transplants into the Developing and Mature Central Nervous System: D S. Sakaguchi, S J. Van Hoffelen, S D. Grozdanic, Y H. Kwon, R H. Kardon, and M J. Young.

13. Stem Cells for Retinal Degenerative Disorders: Jason S. Meyer, Martin L. Katz, and Mark D. Kirk.

14. Magnetic Resonance Tracking of Implanted Adult and Embryonic Stem Cells in Injured Brain and Spinal Cord: Eva Syková and Pavla Jendelová.

15. The Miniature Pig as an Animal Model in Biomedical Research: Petr Vodicka, Karel Smetana, Jr., Barbora Dvoránková, Teresa Emerick, Yingzhi Z. Xu, Jitka Ourednik, Václav Ourednik, and Jan Motlík.

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Part V: Reciprocal Communication between Graft and Host:.

16. Graft/Host Relationships in the Developing and Regenerating CNS of Mammals: Václav Ourednik and Jitka Ourednik.

17. Grafted Neural Stem Cells Shield the Host Environment from Oxidative Stress: Lalitha Madhavan, Václav Ourednik, and Jitka Ourednik.

18. Administration of Allogenic Stem Cells Dosed to Secure Cardiogenesis and Sustained Infarct Repair: Atta Behfar, Denice M. Hodgson, Leonid V. Zingman, Carmen Perez-Terzic, Satsuki Yamada, Garvan C. Kane, Alexey E. Alekseev, Michel Pucéat, and andre Terzic.

Index of Contributors