Preface: Mitchell Eddy and Michael D. Griswold.

Part I: Genomics and Expression Profiling:.

1. Towards Understanding the Core Meiotic Transcriptome in Mammals and its Implications for Somatic Cancer: Frederic Chalmel, Aurelie Lardenois, and Michael Primig.

2. Gene Expression During Development of Fetal and Adult Leydig Cells: Lei Dong, Renshan Ge, Scott A. Jelinsky, Joshua Finger , Daniel S. Johnston , Gregory S. Kopf , Chantal M. Sottas, and Matthew P. Hardy.

3. Identification of Testis-Specific Male Contraceptive Targets: Insights from Transcriptional Profiling of the Cycle of the Rat Seminiferous Epithelium and Purified Testicular Cells: Daniel S. Johnston, Scott A. Jelinsky, Yu Zhi, Joshua N. Finger, Gregory S. Kopf, and William W. Wright.

Part II: Stem Cells and Spermatogonia:.

4. Stem Cell Heterogeneity: Actual and Potential Stem Cell Compartments in Mouse Spermatogenesis: Shosei Yoshida, Yo-Ichi Nabeshima, and Toshinori Nakagawa.

5. Culture and Genetic Modification of Mouse Germline Stem Cells: Mito Kanatsu-Shinohara and Takashi Shinohara.

Part III: Regulation of Gene Expression:.

6. Regulation and Function of the Rhox5 Homeobox Gene: Zhiying Hu, James A. Maclean, Anjana Bhardwaj, and Miles F. Wilkinson.

7. Non-coding RNAs of the Mammalian Testis: The Meiotic Transcripts Nct1 and 2 Encode piRNAs: Naoko Iguchi, Mingang Xu, Tamaki Hori, and Norman B. Hecht.

8. Promoters, Insulators and Regulation of Testis-specific Gene Transcription: Prabhakara P. Reddi, Craig J. Urekar, Mayuresh M. Abhyankar, and Sandeep A. Ranpura.

Part IV: Somatic Cells of the Testis:.

9. Sox8 and Sertoli Cell Function: Claire L. Kennedy, Peter Koopman, Yuji Mishina, and Moira K. O'Bryan.

10. Potential Functions of Retinoic Acid Receptor Alpha in Sertoli Cells and Germ Cells During Spermatogenesis: Timothy J. Doyle, Kirt W. Braun, Derek J. McLean, Raymond W. Wright, Michael D. Griswold, and Kwan Hee Kim.

11. Role of Connexin 43 in Sertoli Cells of Testis: Santhi Sridharan, Ralph Brehm, Martin Bergmann, and Paul S. Cooke.

12. ETV5 is Required for Continuous Spermatogenesis in Adult Mice and May Mediate Blood-Testes Barrier Function and Testicular Immune Privilege: Carla M. K. Morrow, Chris E. Hostetler, Mike D. Griswold, Marie-Claude Hofmann, Kenneth M. Murphy, Paul S. Cooke, and Rex A. Hess.

13. Testicular Morphogenesis: Comparison of In Vivo and In Vitro Models to Study Male Gonadal Development: Kathrin Gassei and Stefan Schlatt.

Part V: Clinical Correlates:.

14. From Gonocytes to Testicular Cancer: The Role of Impaired Gonadal Development: Ewa Rajpert-De Meyts and Christina E. Hoei-Hansen.

15. The Role of Dead-End in Germ Cell Tumor Development: Zhu Rui, Chitralekha Bhattacharya, and Angabin Matin.

16. Chromosomes and Expression in Human Testicular Germ Cell Tumors: Insight into Their Cell of Origin and Pathogenesis: Leendert H.J. Looijenga, Ad J. M. Gillis, Hans J. Stoop, Remko Hersmus, and J. Wolter Oosterhuis