Foreword by H. Sarnat.

Preface

1. Historical background, Paolo Curatolo


2. Diagnostic criteria, Paolo Curatolo


3. Neurological manifestations, Paolo Curatolo and Magda Verdecchia


4. Seizures, Paolo Curatolo and Stefano Seri


5. Intellectual and cognitive impairments, Patrick F. Bolton


6. Autism, Michael Dowling and Paolo Curatolo


7. Neuroimaging, Alessandro Bozzao, Guglielmo Manenti and Paolo Curatolo


8. Positron emission tomography, Eishi Asano, Diane C. Chugani and Harry T. Chugani


9. Dermatologic and stomatologic manifestations, Sergiusz Jozwiak and Robert Schwartz


10. Ophthalmologic manifestations, Sergiusz Jozwiak


11. Renal involvement, Sergiusz Jozwiak


12. Cardiac and vascular involvement, Sergiusz Jozwiak


13. Hepatic, lung, splenic and pancreatic involvement, Sergiusz Jozwiak and Paolo Curatolo


14. Molecular genetics, David J. Kwiatkowski, Mary Pat Reeve, Jeremy P. Cheadle and Julian R. Sampson


15. Neuropathology, Masashi Mizuguchi and Okio Hino


16. Molecular neurobiology, Peter B. Crino


17. Future directions, Paolo Curatolo