 Analgesics: From Chemistry and Pharmacology to Clinical Application
ISBN: 978-3-527-30403-5
Hardcover
613 pages
December 2002
US $315.00
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INTRODUCTION
What is Pain?
PAIN THERAPY TODAY
COX Inhibition: From NSAIDS to Selective Inhibitors
Opioids
Introduction
Opioid Peptides
Synthetic Opioids
Opioids with Clinical Relevance
The delta Opioid Receptor
Opioid-like Receptor (ORL1)
Drug Delivery Systems for Opioids
Noradrenaline and Serotonin Reuptake Inhibitors
NEW APPROACHES IN PAIN THERAPY
Gabapentin and Gabapentinoids
Voltage-gated Ion Channels
Sodium Channels
Potassium Channels
Calcium Channels
Glutamate Receptors
Metabotropic Glutamate Receptors
NMDA Receptors
AMPA and Kainate Receptors
Acetylcholine Receptors
Nicotinic Acetylcholine Receptors
Muscarinic Acetylcholine Receptors
Adenosine in Pain Management
P2 Receptors in Pain
Natural and Synthetic Cannabinoids
Vanilloids and the VR1 Receptor
Substance P/NK1 Receptors
CGRP1 Receptor Antagonists in Pain and Migraine
Nitric Oxide
Outlook-The Future of Pain Management
GLOSSARY
INDEX
What is Pain?
PAIN THERAPY TODAY
COX Inhibition: From NSAIDS to Selective Inhibitors
Opioids
Introduction
Opioid Peptides
Synthetic Opioids
Opioids with Clinical Relevance
The delta Opioid Receptor
Opioid-like Receptor (ORL1)
Drug Delivery Systems for Opioids
Noradrenaline and Serotonin Reuptake Inhibitors
NEW APPROACHES IN PAIN THERAPY
Gabapentin and Gabapentinoids
Voltage-gated Ion Channels
Sodium Channels
Potassium Channels
Calcium Channels
Glutamate Receptors
Metabotropic Glutamate Receptors
NMDA Receptors
AMPA and Kainate Receptors
Acetylcholine Receptors
Nicotinic Acetylcholine Receptors
Muscarinic Acetylcholine Receptors
Adenosine in Pain Management
P2 Receptors in Pain
Natural and Synthetic Cannabinoids
Vanilloids and the VR1 Receptor
Substance P/NK1 Receptors
CGRP1 Receptor Antagonists in Pain and Migraine
Nitric Oxide
Outlook-The Future of Pain Management
GLOSSARY
INDEX
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