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Metal-Catalyzed Cross-Coupling Reactions, 2nd, Completely Revised and Enlarged Edition

ISBN: 978-3-527-30518-6
938 pages
October 2004
Metal-Catalyzed Cross-Coupling Reactions, 2nd, Completely Revised and Enlarged Edition (3527305181) cover image
In this second, completely revised and enlarged edition, Francois Diederich is joined by Armin de Meijere in bringing together in two comprehensive volumes everything of importance related to C-C and C-N cross-coupling reactions.
The range of applications covered extends from the synthesis of complex natural materials via supramolecular chemistry right up to materials science. Internationally renowned experts pass on to the reader the current level of knowledge, while critical analyses of the latest developments and applications allow users to quickly decide for themselves on which strategies are available for solving their synthesis problems. In particular the experimental guidelines for key reactions developed by the authors for the widest possible range of applications testify to the practical advantages this handbook offers every organic chemist.
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Mechanistic Aspects of Metal-Catalyzed C,C- and C,X-Bond Forming Reactions
Metal-Catalyzed Cross-Coupling Reactions of Organoboron Compounds
Organotin Reagents in Cross-Coupling
Organosilicon Compounds in Cross-Coupling Reactions
Cross-Coupling of Organyl Halides with Alkenes -
The Heck Reaction
Cross-Coupling Reactions to sp Carbon Atoms
Carbometallation Reactions
Palladium-Catalyzed 1,4-Additions to Conjugated Dienes
Cross-Coupling Reactions via pi-Allyl Intermediates
Palladium-Catalyzed Coupling Reactions of Propargylic Compounds
Carbon-Carbon Bond Forming Reactions Mediated by Organozinc Reagents
Palladium-Catalyzed Aromatic Carbon-Nitrogen Bond Formation
The Directed ortho-Metalation Cross-Coupling Nexus
Palladium- or Nickel-Catalyzed Cross-Couling with Organometals Containing Zinc, Aluminium, and Zirconium


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Armin de Meijere became Professor of Organic Chemistry at the University of Hamburg in 1977, and took up the same chair at the University of Göttingen in 1989. Since 2006 he is emeritus professor of the University of Göttingen.
Armin de Meijere has been visiting professor at universities in the USA, Israel, Italy, France, as well as at the Indian Institute of Science in Bangalore. He was elected a member of the Norwegian Academy of Sciences and Letters in 1992, and in 1996 received the Alexander von Humboldt-Gay Lussac Prize of the French Ministry for Higher Education and Research. In 1997 he was elected member of the Braunschweigische Wissenschaftliche Gesellschaft, and as an Honorary Professor of the St. Petersburg State University, Russia.
He is editor or member of the Editorial Board for a number of scientific journals, periodicals and books, while his own achievements have been published in over 520 publications.

François Diederich was born in 1952 in Luxembourg. He received his doctorate in 1979 from the University of Heidelberg and subsequently pursued postdoctoral studies at the University of California at Los Angeles (UCLA). After his postdoctoral qualification at the Max-Planck-Institut für medizinische Forschung, he joined the Department of Chemistry and Biochemistry at UCLA in 1985 where he became a full professor four years later. In 1992, he moved to the ETH Zurich as a member of the Department of Chemistry and Applied Biosciences. Professor Diederich's research interests, documented in more than 420 publications, range from medicinal chemistry with a focus on molecular recognition studies, to advanced fullerene and acetylene-based materials with novel optoelectronic properties.
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"... this book provides a very broad and interesting overview of what has been done in the particular field over the last years and every major advance is described and properly referenced. ... The chapters are all written by internationally recognized leaders in the field and are of uniformly high quality providing an excellent insight into the material." Advanced Synthesis & Catalysis

"... will be widely appreciated and should be the book to which researchers refer to expand their knowledge of metal-catalyzed cross-coupling chemistry and its usefulness." Journal of the American Chemical Society

"... covers the important developments in cross-coupling methodology ... highly recommended." CHOICE

"... thoroughly referenced, consistently well written, clear and free from errors ...This is an absolutely essential reference work and it is highly recommended for anyone engaged in the field of organic synthesis."
Applied Organometallic Chemistry

"... a valuable resource for scientists, instructors and graduate students in the areas of organometallic synthesis." E-STREAMS
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