Color Plates.

Part I. Introduction to Concepts and Technologies in Pharmaceutical Biotechnology.

1. A Primer on Pharmaceutical Biotechnology and Industrial Applications (Oliver Kayser, Rainer H. Müller).

2. Procaryotic and Eucaryotic Cells in Biotech Production (Stefan Pelzer, Dirk Hoffmeister, Irmgard Merfort, Andreas Bechthold).

3. Biopharmaceuticals Expressed in Plants (Jörg Knäblein

Part II. Industrial Development and Production Process.

4. Scientific, Technical and Economic Aspects of Vaccine Research and Development (Jens-Peter Gregersen).

5. DNA Vaccines: from Research Tools in Mice to Vaccines for Humans (Jeffrey Ulmer, John Donnelly, Jens-Peter Gregersen).

6. Characterization and Bioanalytical Aspects of Recombinant Proteins as Pharmaceutical Drugs (Jutta Haunschild, Titus Kretzschmar).

7. Biogeneric Drugs (Walter Hinderer).

Part III. Therapeutic Proteins – Special Pharmaceutical Aspects.

8. Pharmacokinetics and Pharmacodynamics of Biotech Drugs (Bernd Meibohm, Hartmut Derendorf).

9 Formulation of Biotech Products (Ralph Lipp, Erno Pungor).

10. Patents in the Pharmaceutical Biotechnology Industry: Legal and Ethical Issues (David B. Resnik).

11. Drug Approval in the European Union and the United States (Gary Walsh).

Part IV. Biotech 21 – Into the Next Decade.

12. Rituximab: Clinical Development of the First Therapeutic Antibody for Cancer (Antonio J. Grillo-López).

13. Somatic Gene Therapy – Advanced Biotechnology Products in Clinical Development (Matthias Schweizer, Egbert Flory, Carsten Muenk, Klaus Cichutek, Uwe Gottschalk).

14. Nonviral Gene Transfer Systems in Somatic Gene Therapy (Oliver Kayser, Albrecht F. Kiderlen).

15. Xenotransplanation in Pharmaceutical Biotechnology (Gregory J. Brunn, Jeffrey L. Platt).

16. Sculpturing the Architecture of Mineralized Tissues: Tissue Engineering of Bone from Soluble Signals to Smart Biomimetic Matrices (Ugo Ripamonti, Lentsha Nathaniel Ramoshebi, Janet Patton, June Teare, Thato Matsaba, Louise Renton).

Index.