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Proteomic and Genomic Analysis of Cardiovascular Disease
ISBN: 978-3-527-30596-4
Hardcover
423 pages
May 2003
US $190.00 Add to Cart

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  • Description
  • Table of Contents
  • Reviews
Preface.

List of Contributors.

Section1: GENOMICS.

Large Scale Expression Profiling in Cardiovascular Disease Using Microarrays: Prospects and Pitfalls (M. Schinke, et al.).

Global Genomic Analyses of Cardiovascular Disease: A Potential Map or Blind Alley? (M. Krenz, et al.). 

Heart Failure: A Genomics Approach (C. Liew).

Principles of cDNA Microarrays as Applied in Heart Failure Research (S. Arab, et al.).

Gene Profiling in the Heart by Subtractive Hybridization (C. Depre).

DNA Mircoarray Gene Profiling: A Tool for the Elucidation of Cardioprotective Genes (E. Murphy, et al.).

Pitfalls Associated with cDNA Microarrays - A Cautionary Tale (A. Aplin & C. Murry).

Application of Biologic Skepticism to Analysis of Expression Phenotypes (L. Adams, et al.).

Genes Involved in Atherosclerosis and Plaque Formation (T. Tuomisto & S. Yl䭈erttuala).

Section 2: PROTEOMICS.

Gene Expression Profiling in Pulmonary and Systemic Vascular Cells Exposed to Biomec hanical Stimuli (S. Ma, et al.).

Proteomics, a Step Beyond Genomics: Applications to Cardiovascular Disease (E. McGregor & M. Dunn).

Mass Spectrometry - A Powerful Analytical Tool (H. Byers & M. Ward).

Differential Expression Proteomic Analysis Using Isotope Coded Affinity Tags (M. Wright & R. Aebersold).

Protein Chip T echnology in Proteomics Analysis (R. Jenkins & S. Pennington).

Recent Applications of Functional Proteomics: Investigations in Smooth Muscle Cell Physiology (J. MacDonald & T. Haystead).

Identification of Targets of Phosphorylation in Heart Mitochondria (R. Gottlieb & H. He).

Proteomic Characterization of Protein Kinase C Signaling Tasks in the Heart (T. Vondriska, et al.).

Identification of Secreted Oxidative Stress-induced Factors (SOXF) and Associated Proteins: Proteomics in Vascular Biology (Z. Jin, et al.).

Myofilament Proteomics: Understanding Contractile Dysfunction in Cardiorespiratory Disease (J. Simpson, et al.).

Section 3: FUTURE PERSPECTIVES.

Genomics Perspective for Drug Discovery (A. Marian & M. Gollob).

Proteomics: A Post-Genomic Platform for Drug Discovery and Development (S. Rapundalo).

Subject Index.