Preface.

Abbreviations.

Chapter 1: Introduction: From the Paper to the Laboratory.

References.

Chapter 2: Tuning-up, Tactical and Strategic Changes.

2.1 Tuning-up Reaction Conditions.

2.2 Tactical Changes.

2.3 Strategic Changes.

References.

Chapter 3: Working with Models.

3.1 (–)-Stenine.

3.2 (+)-Piperazinomycin.

3.3 (+)-Damavaricin D.

3.4 Dynemicin A.

References.

Chapter 4: The Unexpected Reactivity or Inertia of Common Functional Groups.

4.1 Pseudotabersonine.

4.2 Octalactins A and B.

4.3 (–)-Polycavernoside A.

References.

Chapter 5: The Influence of Remote Substituents.

5.1 “Alive” Dead Steric Volume.

5.2 The Reactive Remote Group.

References.

Chapter 6: The Elusive Side Chain.

6.1 (±)-Scopadulcic Acid B.

6.2 Dysidiolide.

6.3 (+)-Epoxydictymene.

6.4 (±)-Lepadiformine.

References.

Chapter 7: The Unpredictable Stereochemistry.

7.1 Nocardiones A and B.

7.2 (±)-Breynolide.

7.3 Hamigerans A and B.

7.4 Calphostin A.

7.5 Fragment C3-C10 of Cytovaricin.

7.6 Goniocin.

References.

Chapter 8: Reluctant Ring Closures.

8.1 Discorhabdin C.

8.2 Discorhabdin A.

8.3 Frondosin B.

8.4 (–)-Laulimalide.

8.5 ent-Rubifolide.

8.6 Roseophilin Tricyclic Core: The Formal Total Synthesis of Roseophilin.

8.7 (–)-Papuamine.

References.

Subject Index.